1,2-Dihexanoyl-sn-glycero-3-PC

1,2-Dihexanoyl-sn-glycero-3-PC Structure
1,2-Dihexanoyl-sn-glycero-3-PC structure
Common Name 1,2-Dihexanoyl-sn-glycero-3-PC
CAS Number 34506-67-7 Molecular Weight 453.50700
Density N/A Boiling Point N/A
Molecular Formula C20H40NO8P Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Advanced lipid systems containing β-carotene: stability under UV-vis radiation and application on porcine skin in vitro.

Phys. Chem. Chem. Phys. 17 , 18710-21, (2015)

Phospholipid-based nanostructures, bicelles and bicosomes, are proposed as carriers of the antioxidant β-carotene. The stability of these nanostructures and their carotenoid cargo was evaluated in an oxidation environment induced by ultraviolet A, visible and...

Structural determination of virus protein U from HIV-1 by NMR in membrane environments.

Biochim. Biophys. Acta 1848 , 3007-18, (2015)

Virus protein U (Vpu) from HIV-1, a small membrane protein composed of a transmembrane helical domain and two α-helices in an amphipathic cytoplasmic domain, down modulates several cellular proteins, including CD4, BST-2/CD317/tetherin, NTB-A, and CCR7. The i...

Molecular dynamics simulations and NMR spectroscopy studies of trehalose-lipid bilayer systems.

Phys. Chem. Chem. Phys. 17 , 22438-47, (2015)

The disaccharide trehalose (TRH) strongly affects the physical properties of lipid bilayers. We investigate interactions between lipid membranes formed by 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and TRH using NMR spectroscopy and molecular dynamics...

Disruption of cytochrome c heme coordination is responsible for mitochondrial injury during ischemia.

Biochim. Biophys. Acta 1847 , 1075-84, (2015)

It was recently suggested that electron flow into cyt c, coupled with ROS generation, oxidizes cyt c Met(80) to Met(80) sulfoxide (Met-O) in isolated hearts after ischemia-reperfusion, and converts cyt c to a peroxidase. We hypothesize that ischemia disrupts ...

Functional and structural evaluation of bovine heart cytochrome c oxidase incorporated into bicelles.

Biochimie 121 , 21-Aug, (2016)

Bilayered long- and short-chain phospholipid assemblies, known as bicelles, have been widely used as model membranes in biological studies. However, to date, there has been no demonstration of structural or functional viability for the fundamental mitochondri...

An NMR investigation of the structure, function and role of the hERG channel selectivity filter in the long QT syndrome.

Biochim. Biophys. Acta 1828(6) , 1494-502, (2013)

The human ether-a-go-go-related gene (hERG) voltage-gated K(+) channels are located in heart cell membranes and hold a unique selectivity filter (SF) amino acid sequence (SVGFG) as compared to other K(+) channels (TVGYG). The hERG provokes the acquired long Q...

A Unique Set of the Burkholderia Collagen-Like Proteins Provides Insight into Pathogenesis, Genome Evolution and Niche Adaptation, and Infection Detection.

PLoS ONE 10 , e0137578, (2015)

Burkholderia pseudomallei and Burkholderia mallei, classified as category B priority pathogens, are significant human and animal pathogens that are highly infectious and broad-spectrum antibiotic resistant. Currently, the pathogenicity mechanisms utilized by ...

Investigating the structural and dynamic properties of n-doxylstearic acid in magnetically-aligned phospholipid bilayers by X-band EPR spectroscopy.

Chem. Phys. Lipids 133(2) , 151-64, (2005)

X-band electron paramagnetic resonance (EPR) spectroscopy has been employed to investigate the dynamic properties of magnetically-aligned phospholipid bilayers (bicelles) based on the molecular order parameters (S(mol)), the hyperfine splitting values and the...

Structural and functional characterization of human apolipoprotein E 72-166 peptides in both aqueous and lipid environments.

J. Biomed. Sci. 18 , 4, (2011)

There are three apolipoprotein E (apoE) isoforms involved in human lipid homeostasis. In the present study, truncated apoE2-, apoE3- and apoE4-(72-166) peptides that are tailored to lack domain interactions are expressed and elucidated the structural and func...

The role of chain rigidity in lipid self-association: comparative study of dihexanoyl- and disorbyl-phosphatidylcholines.

Chem. Phys. Lipids 165(4) , 382-6, (2012)

In the course of structure-function investigations of lipids a phosphatidylcholine molecule with short and rigid tails, di-2,4-hexadienoylphosphatidylcholine (DiSorbPC), was synthesized and studied in comparison with its saturated analog, dihexanoylphosphatid...