Ethacridine lactate Monohydrate

Ethacridine lactate Monohydrate Structure
Ethacridine lactate Monohydrate structure
Common Name Ethacridine lactate Monohydrate
CAS Number 6402-23-9 Molecular Weight 361.392
Density N/A Boiling Point 523.5ºC at 760 mmHg
Molecular Formula C18H23N3O5 Melting Point 243-245 °C(lit.)
MSDS Chinese USA Flash Point 270.4ºC
Symbol GHS07
GHS07
Signal Word Warning

Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells.

MAbs 7(2) , 403-12, (2015)

Linking the heavy chain (HC) and light chain (LC) genes required for monoclonal antibodies (mAb) production on a single cassette using 2A peptides allows control of LC and HC ratio and reduces non-expressing cells. Four 2A peptides derived from the foot-and-m...

Single-step multiresidue determination of ten multiclass veterinary drugs in pork, milk, and eggs using liquid chromatography with tandem mass spectrometry.

J. Sep. Sci. 38 , 2772-80, (2015)

A multiclass, multiresidue determination method is reported for the detection of ten veterinary drugs, including scopolamine, metoclopramide, acriflavine, berberine, tripelennamine, diphenhydramine, acrinol, triamcinolone, loperamide, and roxithromycin in por...

Kinetic and mechanistic analyses of new classes of inhibitors of two-component signal transduction systems using a coupled assay containing HpkA-DrrA from Thermotoga maritima.

Microbiology 150(Pt 4) , 885-96, (2004)

Two-component signal transduction systems (TCSs) play fundamental roles in bacterial survival and pathogenesis and have been proposed as targets for the development of novel classes of antibiotics. A new coupled assay was developed and applied to analyse the ...

Matrix-assisted laser desorption/ionization matrices for negative mode metabolomics.

Eur. J. Mass Spectrom. (Chichester, Eng.) 19(1) , 39-47, (2013)

Matrix-assisted laser desorption/ionization (MALDI) has been shown to be highly sensitive for analyzing low-mass compounds such as metabolites if the right matrix is used. 9-aminoacridine (9AA) is the most commonly employed matrix for negative mode MALDI-MS i...

Termination of second-trimester pregnancy by mifepristone combined with misoprostol versus intra-amniotic injection of ethacridine lactate (Rivanol®): a systematic review of Chinese trials.

Contraception 84(3) , 214-23, (2011)

Mifepristone combined with misoprostol for second-trimester abortion (MM) and intra-amniotic injection of ethacridine lactate (EL; Rivanol®) are the common methods for termination of second-trimester pregnancy in China. The systematic review of relevant liter...

Mifepristone combined with misoprostol versus intra-amniotic injection of ethacridine lactate for the termination of second trimester pregnancy: a prospective, open-label, randomized clinical trial.

Eur. J. Obstet. Gynecol. Reprod. Biol. 151(2) , 149-53, (2010)

To compare the effectiveness and safety of mifepristone/misoprostol versus intra-amniotic injection of ethacridine lactate for the termination of second trimester pregnancy.210 women requesting voluntary termination of pregnancies at between 16 and 24 weeks o...

Influence of topically applied antimicrobial agents on muscular microcirculation.

Ann. Plast. Surg. 67(4) , 407-12, (2011)

Bacterial infections cause major complications in wound healing. Local antiseptics are used for daily wound care; however, their potential toxic effects on the vasculature have not yet been thoroughly investigated. The aim of this study was to assess the effe...

Simultaneous determination of rivanol and mifepristone in human plasma by a HPLC-UV method with solid-phase extraction.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 856(1-2) , 312-7, (2007)

A HPLC method with UV detection was developed and validated for the simultaneous determination of rivanol and mifepristone in human plasma. Norethisterone was used as the internal standard. Separation was performed by a C18 reversed-phase column maintained at...

Randomized study on the effect of adding oxytocin to ethacridine lactate or misoprostol for second-trimester termination of pregnancy.

Acta Obstet. Gynecol. Scand. 85(7) , 825-9, (2006)

To compare effectiveness of misoprostol and ethacridine lactate with or without oxytocin in second-trimester medical abortions.A randomized prospective study. A total of 388 women with genetic indications for termination of pregnancy at 13-24 weeks of gestati...

Intraamniotic ethacridine lactate instillation versus vaginal PGE1 in second trimester termination of pregnancy.

Eur. J. Obstet. Gynecol. Reprod. Biol. 126(2) , 193-6, (2006)

To report on our experience with intraamniotic injection of ethacridine lactate (EL) for second trimester termination of pregnancy (TOP) and to compare its effectiveness with vaginal PGE1 in this setting.(a) Retrospective analysis of 54 intraamniotic EL-induc...