N-Acetyl-Val-Ala-Asp-al

N-Acetyl-Val-Ala-Asp-al Structure
N-Acetyl-Val-Ala-Asp-al structure
Common Name N-Acetyl-Val-Ala-Asp-al
CAS Number 147837-52-3 Molecular Weight 329.349
Density 1.2±0.1 g/cm3 Boiling Point 698.2±55.0 °C at 760 mmHg
Molecular Formula C14H23N3O6 Melting Point N/A
MSDS Chinese USA Flash Point 376.0±31.5 °C

zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation.

Autophagy 7 , 217-228, (2011)

The treatment of L929 fibrosarcoma cells with zVAD has been shown to induce necroptosis. However, whether autophagy is involved or not in this event remains controversial. In this study, we re-examined the role of autophagy in zVAD-induced cell death in L929 ...

Inhibition of human caspases by peptide-based and macromolecular inhibitors.

J. Biol. Chem. 273 , 32608-32613, (1998)

Studies with peptide-based and macromolecular inhibitors of the caspase family of cysteine proteases have helped to define a central role for these enzymes in inflammation and mammalian apoptosis. A clear interpretation of these studies has been compromised b...

Caspase activation by BCR cross-linking in immature B cells: differential effects on growth arrest and apoptosis.

FASEB J. 13 , 931-944, (1999)

The B cell lymphoma WEHI-231 has been used as a model to study immature B cell tolerance, based on its capacity to undergo growth arrest and programmed cell death on B cell receptor (BCR) cross-linking. Using this model to identify the molecular mechanisms un...