(-)-norephedrine
(-)-norephedrine structure
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Common Name | (-)-norephedrine | ||
|---|---|---|---|---|
| CAS Number | 492-41-1 | Molecular Weight | 151.206 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 288.1±20.0 °C at 760 mmHg | |
| Molecular Formula | C9H13NO | Melting Point | 51-53 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 128.1±21.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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Forensic analysis of hallucinogenic mushrooms and khat (Catha edulis Forsk) using cation-exchange liquid chromatography.
Forensic Sci. Int. 195(1-3) , 160-4, (2010) Hallucinogenic mushrooms (e.g. Psilocybe and Panaeolus species) as well as leaves and young shoots of the khat tree (Catha edulis Forsk) are illicit drugs in many countries. The exact concentration of the hallucinogenic alkaloids psilocin and psilocybin in mu... |
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Keep an eye on the pupil: developing countries under chemical attack.
Intern. Emerg. Med. 4(3) , 231-3, (2009)
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The relevance of the urinary concentration of ephedrines in anti-doping analysis: determination of pseudoephedrine, cathine, and ephedrine after administration of over-the-counter medicaments.
Ther. Drug Monit. 31(4) , 520-6, (2009) This article describes a method for the detection and quantitation of cathine, pseudoephedrine, ephedrine, and methylephedrine in urine, using their deuterated analogues as internal standards and derivatization to form the corresponding trimethylsilyl derivat... |
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Cathine, an amphetamine-related compound, acts on mammalian spermatozoa via beta1- and alpha2A-adrenergic receptors in a capacitation state-dependent manner.
Hum. Reprod. 22(3) , 756-65, (2007) Mammalian spermatozoa have been shown to have beta(1,2,3)- and alpha(2A)-adrenergic receptors, the former functioning only in uncapacitated spermatozoa and the latter only in capacitated cells. Cathine, an amphetamine-related metabolite of a compound found in... |
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Determination of urinary concentrations of pseudoephedrine and cathine after therapeutic administration of pseudoephedrine-containing medications to healthy subjects: implications for doping control analysis of these stimulants banned in sport.
Drug Test. Anal. 4(5) , 320-9, (2012) Due to its stimulatory effects on the central nervous system, and its structural similarity to banned stimulants such as ephedrine and methamphetamine, pseudoephedrine (PSE) at high doses is considered as an ergogenic aid for boosting athletic performance. Ho... |
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Analysis of stimulants in oral fluid and urine by gas chromatography-mass spectrometry II: pseudophedrine.
J. Anal. Toxicol. 34(4) , 210-5, (2010) This study was designed to optimize a method for the identification and quantification of ephedrines in oral fluid (OF) and for its application to subjects taking different doses of pseudoephedrine. Ephedrines use by athletes is banned by World Anti-Doping Ag... |
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Extraction and microencapsulation of khat: effects on sexual motivation and estradiol level in female rats.
J. Sex. Med. 6(3) , 682-95, (2009) Khat (Catha edulis) is an evergreen tree/shrub that is thought to affect sexual motivation or libido. Its positive effect on sexual desire is more frequently observed in females than in males and occurs when khat is chewed. Thus, khat's effects on sexual beha... |
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Validation of self-reported khat chewing amongst khat chewers: an exploratory study.
J. Ethnopharmacol. 140(1) , 193-6, (2012) Khat chewing amongst the UK communities originating from Yemen and the East African coast is suggested to create dependency through its main stimulant components (cathinone, norephedrine and norpseudoephedrine) on the central nervous system.To validate self-r... |
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Problems of the use of pseudoephedrine by athletes.
Int. J. Sports Med. 30(8) , 569-72, (2009) Pseudoephedrine (PSE) as a sympathomimetic is an ingredient of many proprietary medicines which are available on the medical market over the counter (OTC drugs). It can be converted to cathine (CATH, norpseudoephedrine) inside the body. Until the end of 2003,... |