1,5-Diaminonaphthalene

1,5-Diaminonaphthalene Structure
1,5-Diaminonaphthalene structure
Common Name 1,5-Diaminonaphthalene
CAS Number 2243-62-1 Molecular Weight 158.200
Density 1.2±0.1 g/cm3 Boiling Point 381.4±22.0 °C at 760 mmHg
Molecular Formula C10H10N2 Melting Point 185-187 °C(lit.)
MSDS Chinese USA Flash Point 220.2±21.8 °C
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning

Flower-like Palladium Nanoclusters Decorated Graphene Electrodes for Ultrasensitive and Flexible Hydrogen Gas Sensing.

Sci. Rep. 5 , 12294, (2015)

Flower-like palladium nanoclusters (FPNCs) are electrodeposited onto graphene electrode that are prepared by chemical vapor deposition (CVD). The CVD graphene layer is transferred onto a poly(ethylene naphthalate) (PEN) film to provide a mechanical stability ...

5-Amino-1-naphthol, a novel 1,5-naphthalene derivative matrix suitable for matrix-assisted laser desorption/ionization in-source decay of phosphorylated peptides.

Rapid Commun. Mass Spectrom. 27(1) , 103-8, (2013)

Although matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD) is an important method for post-translational modification (PTM) analysis, the conventional matrices, 2,5-dihydroxybenzoic acid (2,5-DHB) and 1,5-diaminonaphthalene (1,5-DAN), ar...

Effects of fatty acyl chain length, double-bond number and matrix on phosphatidylcholine responses in matrix-assisted laser desorption/ionization on an Orbitrap mass spectrometer.

Rapid Commun. Mass Spectrom. 29 , 2374-84, (2015)

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is used for the fast qualitative and quantitative analysis of phosphatidylcholines (PC). Fatty acyl chain lengths and the number of double bonds (DB) affect relative responses of PC; hen...

Discrimination of isobaric Leu/Ile residues by MALDI in-source decay mass spectrometry.

J. Am. Soc. Mass Spectrom. 24(2) , 297-300, (2013)

MALDI in-source decay (ISD) has been used for top-down sequencing of proteins. The use of the matrix 1,5-diaminonapthalene (1,5-DAN) gave abundant w ions, which are formed from the unimolecular dissociation of z• radical fragments via α cleavage reaction and ...

Ultraviolet laser induced hydrogen transfer reaction: study of the first step of MALDI in-source decay mass spectrometry.

J. Phys. Chem. B 117(8) , 2321-7, (2013)

The early mechanisms of matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD) are described herein. MALDI-ISD is initiated by the hydrogen transfer from excited matrix molecules to the carbonyl oxygen of the peptide backbone, which is follow...

Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals.

Eur. J. Med. Chem. 44 , 3658-64, (2009)

A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above unwanted property for New Chemical Entities. The dataset was...

Distribution study of atorvastatin and its metabolites in rat tissues using combined information from UHPLC/MS and MALDI-Orbitrap-MS imaging.

Anal. Bioanal. Chem 406(19) , 4601-10, (2014)

The combination of ultrahigh-resolution mass spectrometry imaging (UHRMSI) and ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC/MS/MS) was used for the identification and the spatial localization of atorvastatin (AT) an...

Three Peptide Modulators of the Human Voltage-Gated Sodium Channel 1.7, an Important Analgesic Target, from the Venom of an Australian Tarantula.

Toxins (Basel.) 7 , 2494-513, (2015)

Voltage-gated sodium (NaV) channels are responsible for propagating action potentials in excitable cells. NaV1.7 plays a crucial role in the human pain signalling pathway and it is an important therapeutic target for treatment of chronic pain. Numerous spider...

MALDI imaging reveals lipid changes in the skin of leprosy patients before and after multidrug therapy (MDT).

J. Mass Spectrom. 50 , 1374-85, (2015)

Leprosy still represents a health problem in several countries. Affecting skin and peripheral nerves, it may lead to permanent disabilities. Disturbances on skin lipid metabolism in leprosy were already observed; however, the localization and distribution of ...

MALDI-ISD Mass Spectrometry Analysis of Hemoglobin Variants: a Top-Down Approach to the Characterization of Hemoglobinopathies.

J. Am. Soc. Mass Spectrom. 26 , 1299-310, (2015)

Hemoglobinopathies are the most common inherited disorders in humans and are thus the target of screening programs worldwide. Over the past decade, mass spectrometry (MS) has gained a more important role as a clinical means to diagnose variants, and a number ...