1,8-DIISOCYANATOOCTANE

1,8-DIISOCYANATOOCTANE Structure
1,8-DIISOCYANATOOCTANE structure
Common Name 1,8-DIISOCYANATOOCTANE
CAS Number 10124-86-4 Molecular Weight 196.24600
Density 1.007 g/mL at 25ºC(lit.) Boiling Point 156ºC15 mm Hg(lit.)
Molecular Formula C10H16N2O2 Melting Point N/A
MSDS Chinese USA Flash Point >230 °F
Symbol GHS07
GHS07
Signal Word Warning

Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors.

Bioorg. Med. Chem. Lett. 24(9) , 2193-7, (2014)

A series of inhibitors of the soluble epoxide hydrolase (sEH) containing two urea groups has been developed. Inhibition potency of the described compounds ranges from 2.0 μM to 0.4 nM. 1,6-(Hexamethylene)bis[(adamant-1-yl)urea] (3b) was found to be a potent s...