Pentachlorothiophenol
Pentachlorothiophenol structure
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Common Name | Pentachlorothiophenol | ||
|---|---|---|---|---|
| CAS Number | 133-49-3 | Molecular Weight | 282.402 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 351.3±37.0 °C at 760 mmHg | |
| Molecular Formula | C6HCl5S | Melting Point | 223-227 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 144.6±25.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Sex-related difference in hepatic glutathione conjugation of hexachlorobenzene in the rat.
Toxicol. Appl. Pharmacol. 112(2) , 229-34, (1992) Hexachlorobenzene (HCB) induces hepatic porphyria and liver cancer in female rats, whereas toxicity is minimal in male rats. HCB is biotransformed to sulfur-containing metabolites originating from conjugation to glutathione (GSH). This study aimed to assess d... |
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Effect of estradiol on the induction of porphyria by hexachlorobenzene in the rat.
Biochem. Pharmacol. 54(1) , 19-25, (1997) Hexachlorobenzene (HCB) is porphyrinogenic in adult female but not in male rats. This study aimed to assess the role of 17beta-estradiol in the induction of porphyria by HCB in both sexes by adding or removing the hormone. Groups of intact females, ovariectom... |
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Conversion products of hexachlorobenzene and their role in the disturbance of the porphyrin pathway in rats.
Int. J. Biochem. 12(5-6) , 1003-6, (1980)
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Studies on sex differences in excretion of sulphur derivatives of hexachlorobenzene and pentachloronitrobenzene by rats.
Toxicol. Lett. 56(1-2) , 87-94, (1991) The appearance of sex-related differences in the excretion of sulphur derivatives of hexachlorobenzene (HCB) and pentachloronitrobenzene (PCNB) was studied in vitro and in vivo. Sexually immature rats given HCB showed initially no differences in the excretion... |
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Evaluation of a polyclonal antiserum to pentachlorothiophenol-acetic acid-KLH immunogen: binding properties and use with heterologous PCP derivatives in ELISA for pentachlorophenol.
Anal. Bioanal. Chem 379(3) , 411-8, (2004) A polyclonal antiserum to pentachlorothiophenol-acetic acid-KLH was generated in sheep and assessed by solid phase ELISA. The assessment procedure included use of double checkerboard analysis in the absence and in the presence of analyte loads, estimation of ... |
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Sulphur derivative of hexachlorobenzene in human urine.
Hum. Exp. Toxicol. 11(4) , 271-3, (1992) Pentachlorothiophenol, a sulphur derivative of the widespread environmental pollutant hexachlorobenzene (HCB) has been detected and quantified in the urine of a human general population with high body burden of HCB. The sulphur derivative was analysed by GLC-... |
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Electrical conductivity, transfer of hydrogen ions in lipid bilayer membranes and uncoupling effect induced by pentachlorobenzenethiol (pentachlorothiophenol).
J. Membr. Biol. 76(3) , 227-34, (1983) Pentachlorobenzenethiol (PCBT) has been considered an anomalous uncoupler. It was reported as active in mitochondria, but not effective in inducing electrical conductivity in lipid bilayer membranes. We have overcome the experimental difficulties associated w... |