1,3-Dibromobenzene

1,3-Dibromobenzene Structure
1,3-Dibromobenzene structure
Common Name 1,3-Dibromobenzene
CAS Number 108-36-1 Molecular Weight 235.904
Density 1.9±0.1 g/cm3 Boiling Point 217.5±13.0 °C at 760 mmHg
Molecular Formula C6H4Br2 Melting Point -7 °C
MSDS Chinese USA Flash Point 93.9±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Hepatotoxicity of brominated benzenes: relationship between chemical structure and hepatotoxic effects in acute intoxication of mice.

Arch. Toxicol. 72(2) , 97-103, (1998)

Brominated benzenes appear in the environment and human tissues. Their detection in the environment may be as a result of their usage, e.g. hexabromobenzene (HBB), and as products of HBB degradation or metabolism. The aim of this study was to compare liver im...

Comparison of hepatotoxicity of 1,2-, 1,3- and 1,4-dibromobenzenes: the dynamics of changes of selected parameters of liver necrosis in acute poisoning in mice.

J. Appl. Toxicol. 16(1) , 35-41, (1996)

Various doses of dibromobenzene isomers (1,2-dBB, 1,3-dBB, 1,4-dBB) were administered (i.p.) to BALB mice. The levels of reduced glutathione (GSH) and malondialdehyde (MDA) in the liver, and glutamate-pyruvate transaminase (GPT) (EC.2.6.1.2) gamma-glutamyltra...

Microwave-assisted Suzuki coupling on a KF-alumina surface: synthesis of polyaryls. Microwave-assisted Suzuki coupling on a KF-alumina surface: synthesis of polyaryls. Basu B, et al.

Tetrahedron Lett. 44(19) , 3817-20, (2003)

Synthesis of [n]- and [n.n]cyclophanes by using Suzuki-Miyaura coupling.

J. Org. Chem. 67(15) , 5333-7, (2002)

Reaction of the bis-9-BBN adduct of several dienes with 1,3-dibromobenzene via Suzuki coupling leads to a series of [n]metacyclophanes ranging in size from 10 to 17 atom members. In each case, two carbon-carbon bonds are formed in one reaction vessel. However...

Biochemical alterations as measures of acute and subacute hepatotoxicity of 1,3-dibromobenzene in rat.

Arch. Toxicol. 71(1-2) , 99-106, (1996)

Rats were used to study acute and subacute hepatotoxicity of 1,3-dibromobenzene (1,3-dBB). In the single-exposure experiment, maximum hepatic 1,3-dBB concentrations were found to occur 1 to 12 h after the exposure, depending on the dose. Maximum concentration...

The disposition and metabolism of 1,3-dibromobenzene in the rat.

Chemosphere 39(13) , 2229-38, (1999)

The distribution, excretion and metabolism of 1,3-dibromobenzene following a single i.p. administration to rats 100 or 300 mg/kg was investigated using radiotracer [3H] and GC-MS technique. After 72 hours about 74 to 90% were excreted in urine. The highest ra...