(3-Carboxypropyl)(triphenyl)phosphonium bromide
(3-Carboxypropyl)(triphenyl)phosphonium bromide structure
|
Common Name | (3-Carboxypropyl)(triphenyl)phosphonium bromide | ||
|---|---|---|---|---|
| CAS Number | 17857-14-6 | Molecular Weight | 429.287 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H22BrO2P | Melting Point | 244-247 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Mitochondrial delivery of doxorubicin via triphenylphosphine modification for overcoming drug resistance in MDA-MB-435/DOX cells.
Mol. Pharm. 11(8) , 2640-9, (2014) In this study, doxorubicin (DOX) was conjugated to a lipophilic triphenylphosphonium (TPP) that is selectively taken up by the mitochondrial membrane of cells. This new derivative of DOX, i.e., TPP-DOX, was characterized by infrared spectroscopy (IR), nuclear... |
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