4-Nitro-o-anisidine

4-Nitro-o-anisidine Structure
4-Nitro-o-anisidine structure
Common Name 4-Nitro-o-anisidine
CAS Number 97-52-9 Molecular Weight 168.150
Density 1.3±0.1 g/cm3 Boiling Point 364.2±22.0 °C at 760 mmHg
Molecular Formula C7H8N2O3 Melting Point 140-142 °C(lit.)
MSDS Chinese USA Flash Point 174.0±22.3 °C
Symbol GHS07
GHS07
Signal Word Warning

2-Methoxy-4-nitroaniline is a selective inducer of cytochrome P450IA2 (CYP1A2) in rat liver.

Cancer Lett. 96(1) , 95-8, (1995)

Male F344 rats were treated with a chemical (aniline, nitrobenzene, 2-methoxy-p-phenylenediamine, 2-methoxy-4-nitroaniline or 2-methoxy-4-nitroazobenzene) produced by the azo-reduction and/or N-oxidation of 2-methoxy-4-amino-azo-benzene, a selective inducer o...

Metabolism and disposition of 2-methoxy-4-nitroaniline in male and female Harlan Sprague Dawley rats and B6C3F1/N mice.

Xenobiotica 42(12) , 1213-24, (2012)

The disposition of 2-Methoxy-4-nitroaniline (MNA) was investigated in male and female Harlan Sprague Dawley rats and B6C3F(1)/N mice following oral, intravenous, and dermal exposure to [(14)C]MNA at 2, 15, or 150 mg/kg. Clearance of MNA was investigated in ma...

Use of nitroanilines for spectrophotometric determination of ethinylestradiol in pharmaceutical formulations. Leonardo SG, et al.

Anal. Methods 3(5) , 1198-1201, (2011)