2-Chloro-6-fluorobenzoic acid

2-Chloro-6-fluorobenzoic acid Structure
2-Chloro-6-fluorobenzoic acid structure
Common Name 2-Chloro-6-fluorobenzoic acid
CAS Number 434-75-3 Molecular Weight 174.557
Density 1.5±0.1 g/cm3 Boiling Point 263.7±20.0 °C at 760 mmHg
Molecular Formula C7H4ClFO2 Melting Point 155-157 °C(lit.)
MSDS Chinese USA Flash Point 113.3±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.

Proc. Natl. Acad. Sci. U. S. A. 105 , 9059-64, (2008)

The growing resistance to current first-line antimalarial drugs represents a major health challenge. To facilitate the discovery of new antimalarials, we have implemented an efficient and robust high-throughput cell-based screen (1,536-well format) based on p...

2-Chloro-6-fluoro-benzoic acid.

Acta Crystallogr. Sect. E Struct. Rep. Online 67(Pt 6) , o1329, (2011)

The title compound, C(7)H(4)ClFO(2), is a twofold halogenated derivative of benzoic acid. The C-C-C angles within the aromatic moiety cover a range 116.11 (14)-123.96 (15)°, with the maximum and the minimum value next to each other. In the crystal, O-H⋯O hydr...