N-Acetyl-D-penicillamine

N-Acetyl-D-penicillamine Structure
N-Acetyl-D-penicillamine structure
Common Name N-Acetyl-D-penicillamine
CAS Number 15537-71-0 Molecular Weight 191.25
Density 1.201g/cm3 Boiling Point 392.7ºC at 760mmHg
Molecular Formula C7H13NO3S Melting Point 185-190ºC (dec.)
MSDS Chinese USA Flash Point 191.3ºC
Symbol GHS07
GHS07
Signal Word Warning

Inhibition of a multiproduct terpene synthase from Medicago truncatula by 3-bromoprenyl diphosphates.

Org. Biomol. Chem. 13(16) , 4776-84, (2015)

The multiproduct sesquiterpene synthase MtTPS5 from Medicago truncatula catalyzes the conversion of farnesyl diphosphate (FDP) into a complex mixture of 27 terpenoids. 3-Bromo substrate analogues of geranyl diphosphate (3-BrGDP) and farnesyl diphosphate (3-Br...

A rapid method for determination of 22 selected drugs in human urine by UHPLC/MS/MS for clinical application.

J. AOAC Int. 97(6) , 1526-37, (2015)

A rapid and sensitive ultra-HPLC/MSIMS (UHPLC/MSIMS) assay method for the simultaneous determination in human urine of 22 drugs belonging to different pharmaceutical groups was developed. The drugs were extracted from urine samples and then separated on a Zor...

Occurrence and behavior of the chiral anti-inflammatory drug naproxen in an aquatic environment.

Environ. Toxicol. Chem. 33(12) , 2671-8, (2014)

The present study reports on the occurrence and chiral behavior of the anti-inflammatory drug (S)-naproxen (NAP)-(S)-2-(6-methoxynaphthalen-2-yl)propionic acid-in an aquatic environment under both field and laboratory conditions. In influents and effluents of...

Fabric phase sorptive extraction: a new sorptive microextraction technique for the determination of non-steroidal anti-inflammatory drugs from environmental water samples.

Anal. Chim. Acta 865 , 22-30, (2015)

Fabric phase sorptive extraction (FPSE) is a new, yet very promising member of the sorbent-based sorptive microextraction family. It has simultaneously improved both the extraction sensitivity and the speed of the extraction by incorporating high volume of so...

Type II anti-CD20 mAb-induced lysosome mediated cell death is mediated through a ceramide-dependent pathway.

Biochem. Biophys. Res. Commun. 457(4) , 572-7, (2015)

In the past decade, monoclonal antibodies (mAbs) have revolutionized the treatment of non-Hodgkin lymphomas (NHLs). Although Fc-dependent mechanisms of mAb-mediated tumor clearance have been extensively studied, the ability of mAbs to directly evoke programme...

Determination of Urinary PAH Metabolites Using DLLME Hyphenated to Injector Port Silylation and GC-MS-MS.

J. Anal. Toxicol. 39 , 365-73, (2015)

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants and well-known carcinogens. Hydroxy derivatives of PAH are considered as biomarkers of PAH exposure, and there is a need to measure these metabolites at low concentrations. So, a ...

Olive oil enriched in lycopene from tomato by-product through a co-milling process.

Int. J. Food Sci. Nutr. 66 , 371-7, (2015)

The aim of this investigation was to produce an olive oil (OO) naturally enriched with antioxidants, recovering carotenoids, in particular lycopene, using an industrial by-product of tomato seeds and skin. For this purpose, a technological process in a low-sc...

Dendrimer-functionalized mesoporous silica as a reversed-phase/anion-exchange mixed-mode sorbent for solid phase extraction of acid drugs in human urine.

J. Chromatogr. A. 1392 , 28-36, (2015)

A new dendrimer-functionalized mesoporous silica material based on large-pore 3D cubic Korea Advanced Institute of Science and Technology-6 (KIT-6) was synthesized by the growing of dendritic branches inside the mesopores of aminopropyl functionalized KIT-6. ...

Innovative sampling and extraction methods for the determination of nonsteroidal anti-inflammatory drugs in water.

J. Pharm. Biomed. Anal. 106 , 100-6, (2015)

Two different innovative approaches were used for the determination of nonsteroidal anti-inflammatory drugs (NSAIDs) in water: stir bar sorptive extraction (SBSE) and passive sampling, followed by electrospray ionization liquid chromatography-tandem mass spec...

Secretoneurin gene therapy improves hind limb and cardiac ischaemia in Apo E⁻/⁻ mice without influencing systemic atherosclerosis.

Cardiovasc. Res. 105(1) , 96-106, (2014)

Hypercholesterolaemia is a major risk factor for cardiovascular diseases and has been shown to influence angiogenesis in the hind limb ischaemia (HLI) model. The impaired up-regulation of angiogenic factors seems to be one of the underlying mechanisms for red...