(S)-MCPG

(S)-MCPG Structure
(S)-MCPG structure
Common Name (S)-MCPG
CAS Number 150145-89-4 Molecular Weight 209.19900
Density N/A Boiling Point 425.3ºC at 760mmHg
Molecular Formula C10H11NO4 Melting Point N/A
MSDS USA Flash Point 211ºC

Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones.

Neuropharmacology 32 , 725, (1993)

The (+)-enantiomer of alpha-methyl-4-carboxyphenylglycine (MCPG) stereoslectively antagonized the depolarization of neonatal rat motoneurones and the excitation of rat thalamic neurons induced by the specific metabotropic glutamate receptor agonist (1S,3R)-1-...

Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG.

J. Neurosci. 15 , 87-98, (1995)

Metabotropic glutamate receptors (mGluRs) are critically involved in the maintenance of long-term potentiation (LTP) (Reymann and Matthies, 1989; Behnisch et al., 1991; Izumi et al., 1991; Bashir et al., 1993). In order to assess further the physiological rol...