1,1,1-Trifluoroacetone

1,1,1-Trifluoroacetone Structure
1,1,1-Trifluoroacetone structure
Common Name 1,1,1-Trifluoroacetone
CAS Number 421-50-1 Molecular Weight 112.050
Density 1.2±0.1 g/cm3 Boiling Point 21.5±0.0 °C at 760 mmHg
Molecular Formula C3H3F3O Melting Point -78 °C
MSDS Chinese USA Flash Point -30.6±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis.

Hum. Exp. Toxicol. 33(10) , 1051-65, (2014)

The efficacy of methotrexate (MTX), a widely used chemotherapeutic drug, is limited by its gastrointestinal toxicity and the mechanism of which is not clear. The present study investigates the possible role of mitochondrial damage in MTX-induced enteritis. Sm...

Concise synthesis of enantiopure alpha-trifluoromethyl alanines, diamines, and amino alcohols via the Strecker-type reaction.

J. Org. Chem. 71 , 7075, (2006)

Diastereomerically pure alpha-trifluoromethyl alpha-amino nitriles obtained by Strecker-type reactions from chiral CF3 imines and iminium proved to be very attractive versatile intermediates for the synthesis of various alpha-trifluoromethyl amino compounds. ...

Synthesis , 251, (2007)