1-Naphthalenesulfonic acid

1-Naphthalenesulfonic acid Structure
1-Naphthalenesulfonic acid structure
Common Name 1-Naphthalenesulfonic acid
CAS Number 85-47-2 Molecular Weight 208.234
Density 1.4±0.1 g/cm3 Boiling Point 392ºC
Molecular Formula C10H8O3S Melting Point 77-79 °C(lit.)
MSDS Chinese USA Flash Point 380.2ºC
Symbol GHS05
GHS05
Signal Word Danger

Appearance of annular ring-like intermediates during amyloid fibril formation from human serum albumin.

Phys. Chem. Chem. Phys. 17 , 22862-71, (2015)

The self-assembly of proteins triggered by a conformational switch into highly ordered β-sheet rich amyloid fibrils has captivated burgeoning interest in recent years due to the involvement of amyloids in a variety of human diseases and a diverse range of bio...

Characterization and Higher-Order Structure Assessment of an Interchain Cysteine-Based ADC: Impact of Drug Loading and Distribution on the Mechanism of Aggregation.

Bioconjug. Chem. 27 , 604-15, (2016)

The impact of drug loading and distribution on higher order structure and physical stability of an interchain cysteine-based antibody drug conjugate (ADC) has been studied. An IgG1 mAb was conjugated with a cytotoxic auristatin payload following the reduction...

Molecularly imprinted solid-phase extraction of naphthalene sulfonates from water.

J. Chromatogr. A. 1047(2) , 175-80, (2004)

A new polymeric sorbent synthesised by exploiting molecular imprinting technology has been used to selectively extract naphthalene sulfonates (NSs) directly from aqueous samples. In the non-covalent molecular imprinting approach used to prepare this polymer, ...

Biotransformation of 1-naphthalenesulfonic acid by the green alga Scenedesmus obliquus.

Arch. Microbiol. 167(1) , 32-7, (1997)

Under sulfate limitation, axenic batch cultures of the green alga Scenedesmus obliquus metabolized 1-naphthalenesulfonic acid and partially used the sulfonate as a source of sulfur. The main metabolite, 1-hydroxy-2-naphthalenesulfonic acid, which was not meta...

Double-peak elution profile of a monoclonal antibody in cation exchange chromatography is caused by histidine-protonation-based charge variants.

J. Chromatogr. A. 1424 , 92-101, (2015)

We have systemically investigated unusual elution behaviors of an IgG4 (mAb A) in cation exchange chromatography (CEX). This mAb A exhibited two elution peaks under certain conditions when being purified by several strong CEX columns. When either of the two p...

The biological stimuli for governing the phase transition temperature of the "smart" polymer PNIPAM in water.

Colloids Surf. B Biointerfaces 135 , 588-95, (2015)

A lack of sufficient knowledge regarding the behaviour of stimuli-responsive polymers to biological stimuli hinders the potential use of responsive polymers as biomaterials and medical devices. Hence, in this study, we demonstrate the impact of various globul...