H-Gly-DL-Phe-OH
H-Gly-DL-Phe-OH structure
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Common Name | H-Gly-DL-Phe-OH | ||
|---|---|---|---|---|
| CAS Number | 721-66-4 | Molecular Weight | 222.24000 | |
| Density | 1.259 g/cm3 | Boiling Point | 492.2ºC at 760 mmHg | |
| Molecular Formula | C11H14N2O3 | Melting Point | 273-275℃ (Decomposition) | |
| MSDS | N/A | Flash Point | 251.5ºC | |
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Riboflavin-binding protein is a novel bitter inhibitor.
Chem. Senses 33(1) , 57-63, (2008) Riboflavin-binding protein (RBP) from chicken egg, which was recently reported to be a selective sweet inhibitor for protein sweeteners, was also found to be a bitter inhibitor. RBP elicited broadly tuned inhibition of various bitter substances including quin... |
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Molecular mechanism of the inhibition of cytochrome c aggregation by Phe-Gly.
Arch. Biochem. Biophys. 435(1) , 182-9, (2005) Experimental and computational studies suggest that few general principles govern protein/protein interactions and aggregation. The knowledge of these rules may be exploited to design peptides that are able to interfere with the self-assembly and aggregation ... |
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Intrinsic folding of small peptide chains: spectroscopic evidence for the formation of beta-turns in the gas phase.
J. Am. Chem. Soc. 127(2) , 707-12, (2005) Laser desorption of model peptides coupled to laser spectroscopic techniques enables the gas-phase observation of genuine secondary structures of biology. Spectroscopic evidence for the formation of beta-turns in gas-phase peptide chains containing glycine an... |
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N-peptidyl, O-acyl hydroxamates: comparison of the selective inhibition of serine and cysteine proteinases.
Biochim. Biophys. Acta 1295(2) , 179-86, (1996) Two series of N-aminoacyl, O-benzoyl hydroxamates were designed to investigate the influence of the substituted benzoyl residue on the hydrolytic stability and the reactivity of these potential inhibitors towards selected cysteine and serine proteinases. The ... |
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Covalent immobilisation of protease and laccase substrates onto siloxanes.
Chemosphere 80(8) , 922-8, (2010) Immobilisation of enzyme substrates is a powerful tool in the detection of enzymes in the chemosphere and the environment. A siloxane based strategy for the covalent immobilisation of oxidoreductase and protease substrates was developed involving activation o... |
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Transpeptidation reactions of a specific substrate catalyzed by the streptomyces R61 DD-peptidase: characterization of a chromogenic substrate and acyl acceptor design.
Biochemistry 44(30) , 9971-9, (2005) The Streptomyces R61 dd-peptidase, a functional model for penicillin-binding proteins, catalyzes the hydrolysis and aminolysis of d-alanyl-d-alanine-terminating peptides by specific amines. In vivo, this reaction completes bacterial cell wall biosynthesis. Fo... |
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Transpeptidation reactions of a specific substrate catalyzed by the Streptomyces R61 DD-peptidase: the structural basis of acyl acceptor specificity.
Biochemistry 44(30) , 9961-70, (2005) Bacterial dd-peptidases, the targets of beta-lactam antibiotics, are believed to catalyze d-alanyl-d-alanine carboxypeptidase and transpeptidase reactions in vivo. To date, however, there have been few concerted attempts to explore the kinetic and thermodynam... |
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Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides.
Mol. Pharm. 9(9) , 2761-9, (2012) The oral absorption of some drug substances is mediated by nutrient transporters. As a consequence, nutrients and drugs may compete for available transporters, and interactions at the level of intestinal absorption are possible. Recently, we have identified δ... |
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Gly-L-Phe transport and metabolism across primary cultured rabbit tracheal epithelial cell monolayers.
Pharm. Res. 14(2) , 238-40, (1997)
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The cyanogenic substrate for horseradish peroxidase is a conjugated enamine.
J. Biol. Chem. 262(19) , 9154-9, (1987) We identify the cyanogenic substrate for horseradish peroxidase (HRP) as a conjugated enamine and explore this unusual reaction using alpha-aminocinnamate (RH) as follows. 1) HRP catalyzes the oxidation of RH by O2 (and its peroxidation by H2O2 to form R-R) t... |