Cevimeline hydrochloride hemihydrate
Cevimeline hydrochloride hemihydrate structure
|
Common Name | Cevimeline hydrochloride hemihydrate | ||
|---|---|---|---|---|
| CAS Number | 153504-70-2 | Molecular Weight | 435.09 | |
| Density | 1.19g/cm3 | Boiling Point | 308.5ºC at 760mmHg | |
| Molecular Formula | C20H35ClN2O2S2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 140.4ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Effects of pilocarpine and cevimeline on Ca2+ mobilization in rat parotid acini and ducts.
J. Med. Invest. 56 Suppl , 375, (2009) Previous reports suggested that there is no significant difference in the binding affinity of pilocarpine and cevimeline on muscarinic receptors (1). However, in vivo studies from our laboratory suggested that pilocarpine-induced salivation from the parotid g... |
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Cevimeline enhances the excitability of rat superior salivatory neurons.
J. Med. Invest. 56 Suppl , 267-9, (2009) Cevimeline, a therapeutic drug for xerostomia, is an agonist of muscarinic acetylcholine receptors (mAChRs), and directly stimulates the peripheral mAChRs of the salivary glands. Since cevimeline is distributed in the brain after its oral administration, it i... |
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