A-740003

A-740003 Structure
A-740003 structure
Common Name A-740003
CAS Number 861393-28-4 Molecular Weight 474.555
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C26H30N6O3 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

Disruption in connexin-based communication is associated with intracellular Ca²⁺ signal alterations in astrocytes from Niemann-Pick type C mice.

PLoS ONE 8 , e71361, (2013)

Reduced astrocytic gap junctional communication and enhanced hemichannel activity were recently shown to increase astroglial and neuronal vulnerability to neuroinflammation. Moreover, increasing evidence suggests that neuroinflammation plays a pivotal role in...