Riforal
Riforal structure
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Common Name | Riforal | ||
|---|---|---|---|---|
| CAS Number | 76676-33-0 | Molecular Weight | 384.55200 | |
| Density | 1.12g/cm3 | Boiling Point | 541.7ºC at 760 mmHg | |
| Molecular Formula | C25H36O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 233.6ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Immunochemical demonstration of the mineralocorticoid receptor in ocular tissues.
Neuroendocrinology 65(1) , 70-8, (1997) We studied the presence of the mineralocorticoid receptor (MCR) in the eye with the aid of a number of immunochemical techniques. Immunoblotting with a polyclonal antibody, directed against the rat renal MCR, revealed a single band of about 102 kD in extracts... |
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Immunophotochemical analysis of mineralocortin by polyclonal antibodies against the native receptor from rat kidney.
Biochem. Med. Metab. Biol. 47(2) , 133-44, (1992) We have obtained a polyclonal antiserum by immunizing fawn Burgundy rabbits with the mineralocorticoid receptor (MCR) purified biochemically from rat kidneys. High titers of anti-MCR activity were obtained in radioimmunoassays within 3 weeks and increased wit... |
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The blockade of mineralocorticoid hormone signaling provokes dramatic teratogenesis in cultured rat embryos.
Int. J. Toxicol. 21(3) , 191-9, (2002) Although the administration of adrenocortical hormones to pregnant rats provokes only limited effect on the growth and development of the fetus, the direct influence of these steroids on cultured embryos has never been studied. The disruption of cell signalin... |
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Sound stress activation of tryptophan hydroxylase blocked by hypophysectomy and intracranial RU 38486.
Eur. J. Pharmacol. 256(2) , 177-84, (1994) The rapidly reversible increase in cortical or midbrain tryptophan hydroxylase activity observed ex vivo after exposure of rats to 1-h sound stress was blocked by hypophysectomy, but not sham hypophysectomy, and restored by dexamethasone administration to the... |
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The mineralocorticoid hormone receptor and action in the eye.
Biochem. Biophys. Res. Commun. 219(1) , 150-6, (1996) Immunoblotting with a polyclonal antibody, directed against the mineralocorticoid receptor protein purified from rat kidney in presence of the receptor-specific ligand RU 26752, labeled a single 98-102 kDa band in soluble extracts from bovine retina and from ... |
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Corticosterone is a preferable ligand for measuring rat brain corticosteroid receptors: competition by RU 28362 and RU 26752 for dexamethasone binding in rat hippocampal cytosol.
Brain Res. 625(1) , 84-92, (1993) It is unclear whether in vitro corticosteroid receptor binding assays have used inappropriately high concentrations of synthetic corticosteroid competitors, thereby potentially introducing error into estimates of type I (mineralocorticoid) and type II (glucoc... |
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Rat lung possesses the mineralocorticoid receptor.
Biochem. Biophys. Res. Commun. 183(2) , 405-410, (1992) Lung cytosol from male, adrenalectomized rats was screened for the mineralocorticoid receptor (MCR) by a polyclonal antiserum raised in the rabbit against rat renal antigen. Western blot analysis revealed a single 98 kDa band, like the MCR purified biochemica... |
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Mineralocorticoid hormone action in plant cells.
Biochem. Biophys. Res. Commun. 186(2) , 1102-7, (1992) The multiplication of Chlamydomonas reinhardtii wild type cells can be arrested by the spirolactone RU 26752 and this is fully reversible by the natural mineralocorticoid aldosterone. Evidence is presented for a 52 kDa protein that possesses functional DNA an... |
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Nicotiana tabacum contains a putative mineralocorticoid receptor.
Biochem. Biophys. Res. Commun. 200(3) , 1230-8, (1994) Total protein from N. tabacum cell cytosol, partially purified by ammonium sulphate precipitation, contains a 52 kDa protein that tests positive for mineralocorticoid receptor (MCR)-like activity by Western blots, immuneprecipitation and photochemical cross-l... |
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Paradoxical effects of mineralocorticoids on the ion gated sodium channel in embryologically diverse cells.
Biochem. Biophys. Res. Commun. 270(3) , 811-5, (2000) PCR analysis and Western blotting revealed the expression of the mineralocorticoid receptor (MCR) and the epithelial sodium channel (ENaC) genes at the level of RNA, DNA, and protein in several leukemic cell lines, fibroblasts from human cornea, and epithelia... |