CyPPA

CyPPA Structure
CyPPA structure
Common Name CyPPA
CAS Number 73029-73-9 Molecular Weight 285.387
Density 1.2±0.1 g/cm3 Boiling Point 512.2±42.0 °C at 760 mmHg
Molecular Formula C16H23N5 Melting Point N/A
MSDS Chinese USA Flash Point 263.6±27.9 °C
Symbol GHS07
GHS07
Signal Word Warning

Duration differences of corticostriatal responses in striatal projection neurons depend on calcium activated potassium currents.

Front. Syst. Neurosci. 7 , 63, (2013)

The firing of striatal projection neurons (SPNs) exhibits afterhyperpolarizing potentials (AHPs) that determine discharge frequency. They are in part generated by Ca(2+)-activated K(+)-currents involving BK and SK components. It has previously been shown that...

Identification of the functional binding pocket for compounds targeting small-conductance Ca²⁺-activated potassium channels.

Nat. Commun. 3 , 1021, (2012)

Small- and intermediate-conductance Ca(2+)-activated potassium channels, activated by Ca(2+)-bound calmodulin, have an important role in regulating membrane excitability. These channels are also linked to clinical abnormalities. A tremendous amount of effort ...