Tizanidine hydrochloride

Tizanidine hydrochloride Structure
Tizanidine hydrochloride structure
Common Name Tizanidine hydrochloride
CAS Number 64461-82-1 Molecular Weight 290.17200
Density N/A Boiling Point 391.2ºC at 760 mmHg
Molecular Formula C9H9Cl2N5S Melting Point 280 °C
MSDS USA Flash Point 190.4ºC
Symbol GHS07
GHS07
Signal Word Warning

Spectrophotometric determination of tizanidine and orphenadrine via ion pair complex formation using eosin Y.

Chem. Cent. J. 5 , 60, (2011)

A simple, sensitive and rapid spectrophotometric method was developed and validated for the determination of two skeletal muscle relaxants namely, tizanidine hydrochloride (I) and orphenadrine citrate (II) in pharmaceutical formulations. The proposed method i...

Antihyperalgesic and side effects of intrathecal clonidine and tizanidine in a rat model of neuropathic pain.

Anesthesiology 98 , 1480-1483, (2003)

Although intrathecal clonidine produces pronounced analgesia, antinociceptive doses of intrathecal clonidine produce several side effects, including hypotension, bradycardia, and sedation. Intrathecal tizanidine, another alpha(2)-adrenergic agonist, has provi...