ethylmorphine
ethylmorphine structure
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Common Name | ethylmorphine | ||
|---|---|---|---|---|
| CAS Number | 76-58-4 | Molecular Weight | 313.39100 | |
| Density | 1.31 g/cm3 | Boiling Point | 472.2ºC at 760 mmHg | |
| Molecular Formula | C19H23NO3 | Melting Point | 40-42ºC | |
| MSDS | Chinese USA | Flash Point | 239.4ºC | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
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GCD quantitation of opiates as propionyl derivatives in blood.
J. Anal. Toxicol. 24(2) , 122-6, (2000) We describe a method using a gas chromatograph with electron ionization detection (GCD) for the simultaneous determination of morphine, codeine, 6-monoacetylmorphine, ethylmorphine, and dihydrocodeine in blood. The method employs propionic anhydride in the pr... |
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Urinary excretion of codeine, ethylmorphine, and their metabolites: relation to the CYP2D6 activity.
Ther. Drug Monit. 19(6) , 643-9, (1997) The formation of morphine from codeine and ethylmorphine is mainly mediated by the polymorphic enzyme CYP2D6. The objective of this study was to investigate whether CYP2D6 poor metabolizers (PM) and CYP2D6 extensive metabolizers (EM) would respond differently... |
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Comparison of hepatic and renal drug-metabolising enzyme activities in sheep given single or two-fold challenge infections with Fasciola hepatica.
Int. J. Parasitol. 30(8) , 953-8, (2000) The activity of drug-metabolising enzymes was compared in liver and kidneys of adult sheep given single or two-fold fluke infection. Fascioliasis was induced by oral administration of 200 metacercariae of Fasciola hepatica to female sheep either 10 or 20 week... |
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Inhibitory effects of opioids on compound action potentials in frog sciatic nerves and their chemical structures
Life Sci. 83(5-6) , 198-207, (2008) An opioid tramadol more effectively inhibits compound action potentials (CAPs) than its metabolite mono- O-demethyl-tramadol (M1). To address further this issue, we examined the effects of opioids (morphine, codeine, ethylmorphine and dihydrocodeine) and coca... |
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Evidence for the presence of active cytochrome P450 systems in Schistosoma mansoni and Schistosoma haematobium adult worms.
FEBS Lett. 519(1-3) , 205-9, (2002) Extracts of the adult worms of both Schistosoma mansoni and Schistosoma haematobium can metabolise some typical P450 substrates but to differing degrees. S. mansoni worm extracts displayed a approximately 12-fold higher specific activity for an aminopyrine su... |
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Fatal opiates overdose. Toxicological identification of various metabolites in a blood sample by GC-MS after silylation.
Forensic Sci. Int. 94(3) , 201-9, (1998) A fatal opiates overdose, where ethylmorphine, hydrocodone, dihydrocodeine and codeine were consumed concomitantly, is reported. This case report may contribute to data on fatal blood concentrations of drugs with rare incidence. The relative retention times i... |
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Death of a 10-month-old boy after exposure to ethylmorphine.
J. Forensic Sci. 55(2) , 551-3, (2010) Ethylmorphine, an opiate that is partially metabolized to morphine, is a common ingredient in antitussive preparations. We present a case where a 10-month-old boy was administered ethylmorphine in the evening and found dead in bed the following morning. Postm... |
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Is there a beneficial effect of the calcium channel blocker diltiazem on cyclosporine A nephrotoxicity in rats?
Exp. Toxicol. Pathol. 50(4-6) , 484-90, (1998) To investigate whether or not there is a beneficial effect of diltiazem (D) on cyclosporine A (CsA) nephrotoxicity, renal function, CsA blood levels, and effects of CsA on biotransformation in the liver and on lipid peroxidation were characterized in rats. A ... |
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Interaction of chlormezanone enantiomers with rat liver microsomes.
Eur. J. Drug Metab. Pharmacokinet. 24(1) , 63-8, (1999) Both chlormezanone enantiomers, for the first time obtained by enantiospecific HPLC with a 100% yield, bind to oxidized cytochrome P-450 in rat liver microsomes with a binding curve according to type I, similar to hexobarbital but less pronounced. There are n... |
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General practitioner knowledge of prohibited substances in sport.
Br. J. Sports Med. 31(3) , 259, (1997)
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