Sibutramine hydrochloride monohydrate
Sibutramine hydrochloride monohydrate structure
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Common Name | Sibutramine hydrochloride monohydrate | ||
|---|---|---|---|---|
| CAS Number | 125494-59-9 | Molecular Weight | 334.324 | |
| Density | 1.026 g/cm3 | Boiling Point | 342.6ºC at 760 mmHg | |
| Molecular Formula | C17H29Cl2NO | Melting Point | 193-195.5ºC | |
| MSDS | USA | Flash Point | 161ºC | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
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Simultaneous analysis of amphetamine-type stimulants in plasma by solid-phase microextraction and gas chromatography-mass spectrometry.
J. Anal. Toxicol. 38(7) , 432-7, (2014) Brazil is considered one of the countries with the highest number of amphetamine-type stimulant (ATS) users worldwide, mainly diethylpropion (DIE) and fenproporex (FEN). The use of ATS is mostly linked to diverted prescription stimulants and this misuse is wi... |
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The Expected Net Present Value of Developing Weight Management Drugs in the Context of Drug Safety Litigation.
Pharmacoeconomics 33 , 749-63, (2015) Following withdrawals, failures, and significant litigation settlements, drug product launches in the anti-obesity category slowed despite a large and growing unmet need. Litigation concerns, a more risk-averse regulatory policy, and the difficulty of develop... |
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Effects of diphenyl and p-chloro-diphenyl diselenides on feeding behavior of rats.
Psychopharmacology 232 , 2239-49, (2015) The searching for safe and effective antiobesity drugs has been the subject of intense research. Previous studies have shown several pharmacological applications of organoselenium compounds; however, their possible anorectic-like actions have not been investi... |
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Using a portable ion mobility spectrometer to screen dietary supplements for sibutramine.
J. Pharm. Biomed. Anal. 54(3) , 469-74, (2011) In response to recent incidents of undeclared sibutramine, an appetite suppressant found in dietary supplements, we developed a method to detect sibutramine using hand-held ion mobility spectrometers with an analysis time of 15 s. Ion mobility spectrometry is... |
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Slimmer or fertile? Pharmacological mechanisms involved in reduced sperm quality and fertility in rats exposed to the anorexigen sibutramine.
PLoS ONE 8 , e66091, (2013) Sperm acquire motility and fertility capacity during epididymal transit, under the control of androgens and sympathetic innervations. It is already known that the acceleration of epididymal sperm transit time can lead to lower sperm quality. In a previous wor... |