2,4-Dichlorobenzoyl chloride

2,4-Dichlorobenzoyl chloride Structure
2,4-Dichlorobenzoyl chloride structure
Common Name 2,4-Dichlorobenzoyl chloride
CAS Number 89-75-8 Molecular Weight 209.457
Density 1.5±0.1 g/cm3 Boiling Point 251.8±20.0 °C at 760 mmHg
Molecular Formula C7H3Cl3O Melting Point 28 °C(lit.)
MSDS Chinese USA Flash Point 103.4±22.3 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Synthesis and pharmacological evaluation of a new class of peroxisome proliferator-activated receptor modulators.

Bioorg. Med. Chem. Lett. 12(24) , 3565-7, (2002)

A series of 5-substituted 2-benzoylaminobenzoic acids has been synthesized and assayed for PPARalpha/gamma activity. Both dual activators and selective PPARgamma agonists have been identified. This class of compounds was shown to activate the PPARgamma recept...

NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strainNTB-1 via 2,4-dichlorobenzoyl coenzyme A.

J. Bacteriol. 178(9) , 2656-61, (1996)

Corynebacterium sepedonicum KZ-4, described earlier as a strain capable of growth on 2,4-dichlorobenzoate (G.M. Zaitsev and Y.N. Karasevich, Mikrobiologiya 54:356-369, 1985), is known to metabolize this substrate via 4-hydroxybenzoate and protocatechuate, and...

Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamides.

Bioorg. Med. Chem. Lett. 16(23) , 5968-72, (2006)

This Letter describes the synthesis and SAR, developed through an iterative analog library approach, of potent and selective non-sarcosine-derived GlyT1 inhibitors.