1-Methyl-2-phenylindole
1-Methyl-2-phenylindole structure
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Common Name | 1-Methyl-2-phenylindole | ||
|---|---|---|---|---|
| CAS Number | 3558-24-5 | Molecular Weight | 207.27000 | |
| Density | 1.04 g/cm3 | Boiling Point | 380.8ºC at 760 mmHg | |
| Molecular Formula | C15H13N | Melting Point | 98-100 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 184.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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S-allylcysteine prevents cisplatin-induced nephrotoxicity and oxidative stress.
J. Pharm. Pharmacol. 66(9) , 1271-81, (2014) Cisplatin (CP) is an antineoplastic agent that induces nephrotoxicity and oxidative stress. S-allylcysteine (SAC) is a garlic-derived antioxidant. This study aims to explore whether SAC protects against CP-induced nephrotoxicity in rats.In the first stage, th... |
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Visible Light-Induced Lipid Peroxidation of Unsaturated Fatty Acids in the Retina and the Inhibitory Effects of Blueberry Polyphenols.
J. Agric. Food Chem. 63 , 9295-305, (2015) The lipid peroxidation of unsaturated fatty acids (UFAs) in the retina not only threatens visual cells but also affects the physiological health of the retina. In this work, the potential damages caused by daily visible light exposure on retinal UFAs were eva... |
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Activation of the low molecular weight protein tyrosine phosphatase in keratinocytes exposed to hyperosmotic stress.
PLoS ONE 10(3) , e0119020, (2015) Herein, we provide new contribution to the mechanisms involved in keratinocytes response to hyperosmotic shock showing, for the first time, the participation of Low Molecular Weight Protein Tyrosine Phosphatase (LMWPTP) activity in this event. We reported tha... |
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Reactions of 1-methyl-2-phenylindole with malondialdehyde and 4-hydroxyalkenals. Analytical applications to a colorimetric assay of lipid peroxidation.
Chem. Res. Toxicol. 11(10) , 1176-83, (1998) Under acidic and mild-temperature conditions, 1-methyl-2-phenylindole was found to react with malondialdehyde (MDA) and 4-hydroxyalkenals to yield a stable chromophore with intense maximal absorbance at 586 nm. The use of methanesulfonic acid results in optim... |
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Validation of 1-methyl-2-phenylindole method for estimating lipid peroxidation in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ)Bg (9.).
Pharm. Methods 3(2) , 94-7, (2012) A method using 1-methyl-2-phenylindole was developed for the estimation of lipid peroxidation in third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ)Bg (9). The method is specific for the estimation of malonaldehyde.The larvae were exposed t... |
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Estimation of lipid peroxidation induced by hydrogen peroxide in cultured human lymphocytes.
Dose. Response. 10(1) , 1-10, (2012) Malondialdehyde (MDA) is used for the estimation of damage by reactive oxygen species. MDA is a major reactive aldehyde resulting from the peroxidation of biological membranes. The most common method used to assess MDA production is the thiobarbituric acid (T... |
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Reactions of indoles with nitrogen dioxide and nitrous acid in an aprotic solvent.
Org. Biomol. Chem. 4(17) , 3282-90, (2006) The reaction of 2-phenyl- and 1-methyl-2-phenylindole with nitrogen dioxide or with nitrous acid (NaNO2-CH3COOH) in benzene leads mainly to the formation of the isonitroso and 3-nitroso indole derivatives, respectively. When reacted with nitrous acid, 1-methy... |
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1-Methyl-2-phenyl-3-(1, 3, 4-thiadiazol-2-yldiazenyl)-1H-indole. Seferoglu Z, et al.
Acta Crystallogr. Sect. E Struct. Rep. Online 63(1) , 148-50, (2007)
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3-(5-Ethyl-1, 3, 4-thiadiazol-2-yldiazenyl)-1-methyl-2-phenyl-1H-indole. Seferoglu Z, et al.
Acta Crystallogr. Sect. E Struct. Rep. Online 63(2) , 568-70, (2007)
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Dietary leucine supplementation minimises tumour-induced damage in placental tissues of pregnant, tumour-bearing rats.
BMC Cancer 16 , 58, (2016) The occurrence of cancer during pregnancy merges two complex, poorly understood metabolic and hormonal conditions. This association can exacerbate the conditions of both the mother and the foetus. The branched-chain amino acid leucine enhances cellular activi... |