N-(1-Oxyl-2,2,6,6-tetraMethyl-4-piperidinyl)MaleiMide

N-(1-Oxyl-2,2,6,6-tetraMethyl-4-piperidinyl)MaleiMide Structure
N-(1-Oxyl-2,2,6,6-tetraMethyl-4-piperidinyl)MaleiMide structure
Common Name N-(1-Oxyl-2,2,6,6-tetraMethyl-4-piperidinyl)MaleiMide
CAS Number 15178-63-9 Molecular Weight 251.30200
Density 1.195g/cm3 Boiling Point 376.5ºC at 760mmHg
Molecular Formula C13H19N2O3 Melting Point 91-94ºC
MSDS Chinese USA Flash Point 181.5ºC
Symbol GHS07
GHS07
Signal Word Warning

The Solution Structure of the Lantibiotic Immunity Protein NisI and Its Interactions with Nisin.

J. Biol. Chem. 290 , 28869-86, (2015)

Many Gram-positive bacteria produce lantibiotics, genetically encoded and posttranslationally modified peptide antibiotics, which inhibit the growth of other Gram-positive bacteria. To protect themselves against their own lantibiotics these bacteria express a...

Terpenes increase the lipid dynamics in the Leishmania plasma membrane at concentrations similar to their IC50 values.

PLoS ONE 9(8) , e104429, (2014)

Although many terpenes have shown antitumor, antibacterial, antifungal, and antiparasitic activity, the mechanism of action is not well established. Electron paramagnetic resonance (EPR) spectroscopy of the spin-labeled 5-doxyl stearic acid revealed remarkabl...

A novel analytical method to evaluate directly catalase activity of microorganisms and mammalian cells by ESR oximetry.

Free Radic. Res. 44(9) , 1036-43, (2010)

Electron spin resonance (ESR) oximetry technique was applied for analysis of catalase activity in the present study. Catalase activity was evaluated by measuring oxygen from the reaction between hydrogen peroxide (H(2)O(2)) and catalase-positive cells. It was...

Cytotoxicity of commonly used nitroxide radical spin probes.

Life Sci. 40(5) , 495-8, (1987)

Since nitroxide radical spin probes are used frequently to test biophysical properties of cells, their use should be restricted to conditions that do not perturb normal cell growth and viability. Eight commonly used nitroxide radical spin probes have been tes...

The study of the quercetin action on human erythrocyte membranes.

Biochem. Pharmacol. 66(4) , 605-12, (2003)

Quercetin is a naturally occurring flavonoid that exerts multiple pharmacological effects. In our previous study, we showed that quercetin greatly affects the lipid membrane. In this report, a study of quercetin on human erythrocyte membrane has been performe...

The effect of bile salts and calcium on isolated rat liver mitochondria.

Biochim. Biophys. Acta 1453(3) , 396-406, (1999)

Intact mitochondria were incubated with and without calcium in solutions of chenodeoxycholate, ursodeoxycholate, or their conjugates. Glutamate dehydrogenase, protein and phospholipid release were measured. Alterations in membrane and organelle structure were...

In vitro and ex vivo effect of hyaluronic acid on erythrocyte flow properties.

J. Biomed. Sci. 17 , 8, (2010)

Hyaluronic acid (HA) is present in many tissues; its presence in serum may be related to certain inflammatory conditions, tissue damage, sepsis, liver malfunction and some malignancies. In the present work, our goal was to investigate the significance of hyal...

Irreversible adsorption of human serum albumin to hydrogel contact lenses: a study using electron spin resonance spectroscopy.

Biomaterials 20(14) , 1345-56, (1999)

Human serum albumin (HSA) was specifically spin labelled with 4-maleimido-tempo (MSL) at its cysteine 34 residue (HSA-MSL). The irreversible adsorption of HSA-MSL to hydrogel contact lenses (etafilcon A, tefilcon and vifilcon A) was investigated using electro...

Molecular changes in erythrocyte membranes induced by nitroimidazoles and radiation.

Pol. J. Pharmacol. 48 , 269, (1996)

A damage of erythrocyte membranes by gamma-irradiation in the presence of nitroimidazole derivatives was shown by the demonstration of their effect on lipid peroxidation and SDS-PAGE protein pattern (1000 Gy) as well as on electron spin resonance (ESR) spectr...

Effect of exogenous and endogenous antioxidants on 3-nitropionic acid-induced in vivo oxidative stress and striatal lesions: insights into Huntington's disease.

J. Neurochem. 75(4) , 1709-15, (2000)

3-Nitropropionic acid (3-NP) is an irreversible inhibitor of complex II in the mitochondria. 3-NP toxicity has gained acceptance as an animal model of Huntington's disease (HD). In the present study, we confirmed that rats injected with 3-NP (20 mg/kg, i.p., ...