Cyclobenzaprine hydrochloride
Cyclobenzaprine hydrochloride structure
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Common Name | Cyclobenzaprine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 6202-23-9 | Molecular Weight | 311.848 | |
| Density | N/A | Boiling Point | 405.9ºC at 760 mmHg | |
| Molecular Formula | C20H22ClN | Melting Point | 216-218ºC | |
| MSDS | Chinese USA | Flash Point | 9℃ | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
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Fast targeted analysis of 132 acidic and neutral drugs and poisons in whole blood using LC-MS/MS.
Forensic Sci. Int. 243 , 35-43, (2014) The aim of this study was to develop an LC-MS/MS based screening technique that covers a broad range of acidic and neutral drugs and poisons by combining a small sample volume and efficient extraction technique with simple automated data processing. After pro... |
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Medications as a potential source of exposure to phthalates among women of childbearing age.
Reprod. Toxicol. 37 , 1-5, (2013) To evaluate the association between the use of medications potentially containing phthalates and urinary concentrations of specific phthalate metabolites around conception.Women enrolled in the Environment and Reproductive Health project from 2006 to 2009 com... |
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Patient education and self-care for the management of jaw pain upon awakening: a randomized controlled clinical trial comparing the effectiveness of adding pharmacologic treatment with cyclobenzaprine or tizanidine.
J. Oral Facial Pain Headache 28(2) , 119-27, (2014) To compare the effectiveness of adding cyclobenzaprine, tizanidine, or placebo to patient education and a self-care management program for patients with myofascial pain and specifically presenting with jaw pain upon awakening.Forty-five patients with a diagno... |
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Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone.
Clin. Ther. 26(9) , 1355-67, (2004) Low back pain is a leading reason for primary care visits. Many treatment options are available, but some lack scientific support.The aim of this review was to discuss the etiology of low back pain and the relative risks and benefits of muscle relaxants commo... |
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Efficacy and tolerability of cyclobenzaprine extended release for acute muscle spasm: a pooled analysis.
Postgrad. Med. 122(4) , 158-69, (2010) To assess the efficacy and tolerability of once-daily cyclobenzaprine extended release (CER) 15 and 30 mg in relieving acute muscle spasm.This is a pooled analysis of 2 randomized, double-blind, placebo-controlled, parallel-group studies of identical design. ... |
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Time to recovery in patients with acute painful musculoskeletal conditions treated with extended-release or immediate-release cyclobenzaprine.
Adv. Ther. 28(4) , 295-303, (2011) This post-hoc analysis examined time to recovery in patients with acute, painful musculoskeletal conditions following cyclobenzaprine extended release (CER; AMRIX(®), Cephalon, Inc., Frazer, PA, USA), cyclobenzaprine immediate release (CIR; Flexeril(®), Pliva... |
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Pharmacokinetic profile of once-daily cyclobenzaprine extended-release.
Expert Opin. Drug Metab. Toxicol. 6(11) , 1425-36, (2010) Cyclobenzaprine immediate-release (CIR) is a widely prescribed skeletal muscle relaxant with an established efficacy and safety profile in patients with muscle spasm associated with acute, painful conditions, although it is commonly associated with sedation. ... |
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Microsized graphite sensors for potentiometric determination of cyclobenzaprine hydrochloride in pure powder, tablets, and plasma.
J. AOAC Int. 94(6) , 1807-14, (2011) Two cyclobenzaprine hydrochloride (CZ) microsized graphite selective sensors were investigated with dibutylsebacate as a plasticizer in a polymeric matrix of carboxylated polyvinyl chloride (PVC-COOH) in the case of sensor 1, based on the interaction between ... |
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Determination of cyclobenzaprine in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry and its application in a pharmacokinetic study.
Biomed. Chromatogr. 26(9) , 1083-8, (2012) A sensitive, rapid and simple liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS/MS) method was developed for the quantitative determination of cyclobenzaprine in human plasma, to study the pharmacokinetic behavior of cyclobenzaprine c... |
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Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): typical clinical and neuroimaging features in a Brazilian family.
Arq. Neuropsiquiatr. 69(2B) , 288-91, (2011) Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disorder characterized by late-infantile onset spastic ataxia and other neurological features. ARSACS has a high prevalence in northeastern Quebec, Canada. Several ARSAC... |