L-Anserine · nitrate

L-Anserine · nitrate Structure
L-Anserine · nitrate structure
Common Name L-Anserine · nitrate
CAS Number 10030-52-1 Molecular Weight 303.272
Density N/A Boiling Point 611.3ºC at 760mmHg
Molecular Formula C10H17N5O6 Melting Point 226-228ºC
MSDS Chinese USA Flash Point 323.5ºC
Symbol GHS07
GHS07
Signal Word Warning

E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish.

Nutr. Metab. 12 , 17, (2015)

Diet-induced hepatic steatosis is highly associated with nonalcoholic fatty liver disease, which is related to the development of metabolic syndrome. While advanced stage nonalcoholic hepatic steatosis and steatohepatitis (NASH) result ultimately in fibrosis ...

Carnosine treatment largely prevents alterations of renal carnosine metabolism in diabetic mice.

Amino Acids 42(6) , 2411-6, (2011)

Recently, we identified an allelic variant of human carnosinase 1 (CN1) that results in increased enzyme activity and is associated with susceptibility for diabetic nephropathy in humans. Investigations in diabetic (db/db) mice showed that carnosine ameliorat...

Anserine inhibits carnosine degradation but in human serum carnosinase (CN1) is not correlated with histidine dipeptide concentration.

Clin. Chim. Acta 412 , 263-267, (2011)

We reported an association of a particular allele of the carnosinase (CNDP1 Mannheim) gene with reduced serum carnosinase (CN1) activity and absence of nephropathy in diabetic patients. Carnosine protects against the adverse effects of high glucose levels but...

Anserine syndrome.

Rev. Bras. Reumatol. 50 , 313-327, (2010)

Knee pain is a common complaint in clinical practice, and pes anserinus tendino-bursitis syndrome (PATB) has been frequently diagnosed based only on clinical features that may cause equivocal interpretations. Patients complain of characteristic spontaneous me...

Effect of anserine ingestion on hyperglycemia and the autonomic nerves in rats and humans.

Nutr. Neurosci. 13 , 183-188, (2010)

Anserine and L-carnosine are similar dipeptides synthesized by muscles of vertebrates. The functional role of anserine is unknown, although previous studies showed hypoglycemic effects of carnosine through autonomic nerves. Thus, we evaluated the effects of a...

Measurement of carnosine, homocarnosine and anserine by FASI capillary electrophoresis UV detection: applications on biological samples.

Talanta 84 , 931-935, (2011)

A field amplified sample injection (FASI) capillary electrophoresis method with UV detection was developed for the separation and detection of carnosine-related peptides carnosine (Car), anserine (Ans) and homocarnosine (Hcar). The imidazole dipeptides were b...

The bioactive dipeptide anserine is transported by human proton-coupled peptide transporters.

FEBS J. 277 , 790-795, (2010)

The bioactive dipeptide derivative anserine (beta-alanyl-1-N-methyl-L-histidine) is absorbed from the human diet in intact form at the intestinal epithelium. The purpose of this study was to investigate whether anserine is a substrate of the H(+)/peptide cotr...

Effect of anserine ingestion on the hyperglycemia and autonomic nerves in rats and humans. Kubomura D, Matahira Y, Nagai K, Niijima A.

Nutr. Neurosci. 13 , 1230128, (2010)