dexamethasone isonicotinate

dexamethasone isonicotinate Structure
dexamethasone isonicotinate structure
Common Name dexamethasone isonicotinate
CAS Number 2265-64-7 Molecular Weight 497.55500
Density 1.34 g/cm3 Boiling Point 676ºC at 760 mmHg
Molecular Formula C28H32FNO6 Melting Point 256°C
MSDS N/A Flash Point 362.6ºC

Glucose concentrations in plasma and urine after glucocorticoid injection in healthy cows.

Nord. Vet. Med. 34(4-5) , 143-6, (1982)

Dexamethasone isonicotinate inhibits dual and late asthmatic reactions but not the increase of airway responsiveness induced by toluene diisocyanate in sensitized subjects.

Ann. Allergy 63(4) , 292-6, (1989)

To determine whether treatment with aerosolized dexamethasone isonicotinate inhibits asthmatic reactions and the associated increase in airway responsiveness induced by toluene diisocyanate (TDI), we studied six sensitized subjects with previously demonstrate...

Effect of dexamethasone isonicotinate on milk yield in ketotic cows.

Vet. Rec. 128(18) , 427, (1991)

A comparison of botulinum toxin a and intralesional steroids for the treatment of plantar fasciitis: a randomized, double-blinded study.

Foot Ankle Int. 34(1) , 8-14, (2013)

The objective of this study was to compare intramuscularly applied botulinum toxin A (BTX-A) in the gastroc-soleus complex with intralesional steroids for the treatment of plantar fasciitis.The patients were randomly divided into 2 groups according to the tre...

Action of dexamethasone in an equine model of acute non-immune inflammation.

Res. Vet. Sci. 48(1) , 87-95, (1990)

In a crossover study in seven New Forest ponies the actions of dexamethasone, at a dose rate of 0.06 mg kg-1 administered intravenously, were compared with those of a placebo treatment. Dexamethasone exerted expected effects on plasma and inflammatory exudate...

A selective LC/RIA for dexamethasone and its prodrug dexamethasone-21-isonicotinate in biological fluids.

J. Pharm. Biomed. Anal. 9(9) , 761-7, (1991)

A combined LC/RIA procedure is described for the selective determination of dexamethasone (DEX) and its prodrug dexamethasone-21-isonicotinate (DIN) in plasma. The low affinity of the employed dexamethasone antiserum for DIN (cross-reactivity less than 0.5%) ...

Adrenocorticotropin-corticosterone relationship during dexamethasone therapy in 17 alpha-hydroxylase deficiency.

Horm. Metab. Res. 24(7) , 339-41, (1992)

A previous study in an untreated girl with 17 alpha-hydroxylase deficiency syndrome (17-OHDS) indicated that in the absence of cortisol production, ACTH and corticosterone (B) may interact to modulate the brain-pituitary-adrenocortical system. The ACTH-B inte...

[Effects of a single dose of dexamethasone-21-isonicotinate on the phagocytosis performance of neutrophilic granulocytes and monocytes in periparturient dairy cows].

Berl. Munch. Tierarztl. Wochenschr. 118(3-4) , 140-9, (2005)

The objective of the study was to describe the effects of a short acting glucocorticoid which was administered immediately after parturition in dairy cows on haematological, immunologic and metabolic parameters. The study was performed on 104 cows, 52 cows re...

Dexamethasone-isonicotinate aerosol in the long-term treatment of steroid-dependent asthmatic children.

Med. Interne 18(2) , 203-10, (1980)

Dexamethasone-isonicotinate aerosol (DIA) was administered to twenty-nine steroid-dependent children with chronic perennial asthma, in an open trial during one year. An attempt was made to withdraw systemic corticosteroid therapy. As judged by clinical result...

[Notes on the disaster in Bhopal].

Dtsch. Med. Wochenschr. 110(45) , 1749-51, (1985)