H-Cys-Gly-OH
H-Cys-Gly-OH structure
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Common Name | H-Cys-Gly-OH | ||
|---|---|---|---|---|
| CAS Number | 19246-18-5 | Molecular Weight | 178.210 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 459.0±45.0 °C at 760 mmHg | |
| Molecular Formula | C5H10N2O3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 231.4±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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A quantitative metabolomics peek into planarian regeneration.
Analyst 140 , 3445-64, (2015) The fresh water planarian species Schmidtea mediterranea is an emerging stem cell model because of its capability to regenerate a whole animal from a small piece of tissue. It is one of the best model systems to address the basic mechanisms essential for rege... |
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Increase in the protein-bound form of glutathione in human blood after the oral administration of glutathione.
J. Agric. Food Chem. 62(26) , 6183-9, (2014) The present study examined the impact of the supplementation of glutathione (GSH), γ-L-glutamyl-L-cysteinyl-glycine, on human blood GSH levels. Healthy human volunteers were orally supplemented with GSH (50 mg/kg body weight). Venous blood was collected from ... |
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Hydrogen exchange equilibria in thiols.
Chem. Res. Toxicol. 25(9) , 1862-7, (2012) Cysteine, cysteinyl-glycine, glutathione, phenylalanyl-cysteinyl-glycine, and histidyl-cysteinyl-glycine were dissolved in acidic and neutral D(2)O in the presence of the radical generator 2,2'-azobis(2-methylpropionamidine) dihydrochloride and radical mediat... |
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Simultaneous determination of albumin and low-molecular-mass thiols in plasma by HPLC with UV detection.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 981-982 , 57-64, (2015) In this paper, we describe a simple and robust HPLC based method for determination of total low- and high-molecular-mass thiols, protein S-linked thiols and reduced albumin in plasma. The method is based on derivatization of analytes with 2-chloro-1-methylqui... |
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Cysteinyl-glycine reduction as marker for levodopa-induced oxidative stress in Parkinson's disease patients.
Mov. Disord 26 , 543-546, (2011) Oxidative stress is influenced by the thiol homeostasis, which determines the redox milieu. One of its components is Cysteinyl-glycine (Cys-Gly) generation, as its metabolic precursor is the free radicals scavenging glutathione. Levodopa is under suspicion to... |
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Dug1p Is a Cys-Gly peptidase of the gamma-glutamyl cycle of Saccharomyces cerevisiae and represents a novel family of Cys-Gly peptidases.
J. Biol. Chem. 284 , 14493-14502, (2009) GSH metabolism in yeast is carried out by the gamma-glutamyl cycle as well as by the DUG complex. One of the last steps in the gamma-glutamyl cycle is the cleavage of Cys-Gly by a peptidase to the constitutent amino acids. Saccharomyces cerevisiae extracts ca... |
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From cysteine to longer chain thiols: thermodynamic analysis of cadmium binding by phytochelatins and their fragments.
Metallomics 3 , 838-846, (2011) Isothermal Titration Calorimetry (ITC) was used to study the binding of Cd(2+) by phytochelatins ((γGlu-Cys)(n)-Gly, PC(n); n = 1-5) and their selected fragments (Cys, Cys-Gly and γGlu-Cys) in order to understand the influence of the chain length on the compl... |
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Cys-Gly specific dipeptidase Dug1p from S. cerevisiae binds promiscuously to di-, tri-, and tetra-peptides: Peptide-protein interaction, homology modeling, and activity studies reveal a latent promiscuity in substrate recognition.
Biochimie 93 , 175-186, (2011) Dug1p is a recently identified novel dipeptidase and plays an important role in glutathione (GSH) degradation. To understand the mechanism of its substrate recognition and specificity towards Cys-Gly dipeptides, we characterized the solution properties of Dug... |
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Human organic anion transporter OAT1 is not responsible for glutathione transport but mediates transport of glutamate derivatives.
Am. J. Physiol. Renal Physiol. 304(4) , F403-9, (2013) Due to their clearance function, the kidneys are exposed to high concentrations of oxidants and potentially toxic substances. To maintain cellular integrity, renal cells have to be protected by sufficient concentrations of the antioxidant glutathione (GSH). W... |
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Role of Aggregatibacter actinomycetemcomitans in glutathione catabolism.
Oral Microbiol. Immunol. 24(3) , 236-42, (2009) Our previous studies demonstrated that three enzymes, gamma-glutamyltransferase (GGT), cysteinylglycinase (CGase) and cystalysin, are required for the catabolism of glutathione to produce hydrogen sulfide (H(2)S) in Treponema denticola. In this study, we exam... |