![]() Disodium succinate structure
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Common Name | Disodium succinate | ||
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CAS Number | 150-90-3 | Molecular Weight | 162.052 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C4H4Na2O4 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 110.9ºC |
Oxidative damage of rat liver mitochondria during exposure to t-butyl hydroperoxide. Role of Ca²⁺ ions in oxidative processes.
Life Sci. 92(23) , 1110-7, (2013) The present study was designed for further evaluation of the biochemical mechanism of hepatic mitochondrial dysfunction under oxidative damages induced by organic hydroperoxide, tert-butyl hydroperoxide (tBHP), for estimation of the molecular targets impaired... |
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Toxicity of copper on isolated liver mitochondria: impairment at complexes I, II, and IV leads to increased ROS production.
Cell Biochem. Biophys. 70(1) , 367-81, (2014) Oxidative damage has been implicated in disorders associated with abnormal copper metabolism and also Cu(2+) overloading states. Besides, mitochondria are one of the most important targets for Cu(2+), an essential redox transition metal, induced hepatotoxicit... |
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Phenotype consequences of myophosphorylase dysfunction: insights from the McArdle mouse model.
J. Physiol. 593 , 2693-706, (2015) This is the first study to analyse the effect of muscle glycogen phosphorylase depletion in metabolically different muscle types. In McArdle mice, muscle glycogen phosphorylase is absent in both oxidative and glycolytic muscles. In McArdle mice, the glycogen ... |
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Bacteriophages of wastewater foaming-associated filamentous Gordonia reduce host levels in raw activated sludge.
Sci. Rep. 5 , 13754, (2015) Filamentous bacteria are a normal and necessary component of the activated sludge wastewater treatment process, but the overgrowth of filamentous bacteria results in foaming and bulking associated disruptions. Bacteriophages, or phages, were investigated for ... |
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C-phycocyanin prevents cisplatin-induced mitochondrial dysfunction and oxidative stress.
Mol. Cell Biochem. 406 , 183-97, (2015) The potential of C-phycocyanin (C-PC) to prevent cisplatin (CP)-induced kidney mitochondrial dysfunction was determined in CD-1 male mice. The CP-induced mitochondrial dysfunction was characterized by ultrastructural abnormalities and by decrease in the follo... |
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Cecal succinate elevated by some dietary polyphenols may inhibit colon cancer cell proliferation and angiogenesis.
J. Agric. Food Chem. 62(24) , 5589-94, (2014) This study demonstrated that 0.5% dietary rutin, ellagic acid, or curcumin markedly increased cecal succinate levels in rats fed a high-fat diet, whereas catechin, caffeic acid, and quercetin did not. Other organic acids were modestly or hardly affected by po... |
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Frequencies of myohistological mitochondrial changes in patients with mitochondrial DNA deletions and the common m.3243A>G point mutation.
Neuropathology 35(2) , 130-6, (2015) Frequencies of typical myohistological changes such as ragged red fibers (RRF) and cytochrome c oxidase (COX)-deficient fibers have been suggested to be dependent on underlying mitochondrial DNA (mtDNA) defect. However, there are no systematic studies compari... |
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A high-performance liquid chromatography-tandem mass spectrometry-based targeted metabolomics kidney dysfunction marker panel in human urine.
Clin. Chim. Acta 446 , 43-53, (2015) Previous studies have examined and documented fluctuations in urine metabolites in response to disease processes and drug toxicity affecting glomerular filtration, tubule cell metabolism, reabsorption, oxidative stress, purine degradation, active secretion an... |
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Retro-translocation of mitochondrial intermembrane space proteins.
Proc. Natl. Acad. Sci. U. S. A. 112 , 7713-8, (2015) The content of mitochondrial proteome is maintained through two highly dynamic processes, the influx of newly synthesized proteins from the cytosol and the protein degradation. Mitochondrial proteins are targeted to the intermembrane space by the mitochondria... |
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Acquired resistance to gemcitabine and cross-resistance in human pancreatic cancer clones.
Anticancer Drugs 26(1) , 90-100, (2014) The efficacy of gemcitabine (GEM), a standard treatment agent for pancreatic cancer, is insufficient because of primary or acquired resistance to this drug. Patients with tumors intrinsically sensitive to GEM gradually acquire resistance and require a shift t... |