GMP disodium salt
GMP disodium salt structure
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Common Name | GMP disodium salt | ||
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| CAS Number | 5550-12-9 | Molecular Weight | 407.184 | |
| Density | N/A | Boiling Point | 890.2ºC at 760 mmHg | |
| Molecular Formula | C10H12N5Na2O8P | Melting Point | 300°C | |
| MSDS | USA | Flash Point | 492.2ºC | |
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A novel surface-confined glucaminium-based ionic liquid stationary phase for hydrophilic interaction/anion-exchange mixed-mode chromatography.
J. Chromatogr. A. 1360 , 240-7, (2014) Glucaminium-based ionic liquids are a new class of recently developed ionic liquids and prepared by functionalizing the amine group of N-methyl-d-glucamine, which renders them good hydrophilicity due to the presence of the glucose structure and charged quater... |
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Highly and Broad-Spectrum In Vitro Antitumor Active cis-Dichloridoplatinum(II) Complexes with 7-Azaindoles.
PLoS ONE 10 , e0136338, (2015) The cis-[PtCl2(naza)2] complexes (1-3) containing monosubstituted 7-azaindole halogeno-derivatives (naza), showed significantly higher activity than cisplatin towards ovarian carcinoma A2780, its cisplatin-resistant variant A2780R, osteosarcoma HOS, breast ca... |
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Assessment of capillary anion exchange ion chromatography tandem mass spectrometry for the quantitative profiling of the phosphometabolome and organic acids in biological extracts.
J. Chromatogr. A. 1370 , 70-9, (2014) Metabolic profiling has become an important tool in biological research, and the chromatographic separation of metabolites coupled with mass spectrometric detection is the most frequently used approach for such studies. The establishment of robust chromatogra... |
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Development and validation of a transcreener assay for detection of AMP- and GMP-producing enzymes.
Assay Drug Dev. Technol. 8(3) , 344-55, (2010) Screening of AMP- and GMP-producing enzymes such as phosphodiesterases (PDEs), ligases, and synthetases would be simplified by the ability to directly detect unmodified nucleoside monophosphates. To address this need, we developed polyclonal and monoclonal an... |
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Effects of 3 weeks GMP oral administration on glutamatergic parameters in mice neocortex.
Purinergic Signal. 8(1) , 49-58, (2011) Overstimulation of the glutamatergic system (excitotoxicity) is involved in various acute and chronic brain diseases. Several studies support the hypothesis that guanosine-5'-monophosphate (GMP) can modulate glutamatergic neurotransmission. The aim of this st... |
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Neurotoxicity induced by glutamate in glucose-deprived rat hippocampal slices is prevented by GMP.
Neurochem. Res. 30 , 83-89, (2005) Guanosine-5'-monophosphate (GMP) was evaluated as a neuroprotective agent against the damage induced by glutamate in rat hippocampal slices submitted to glucose deprivation. In slices maintained under physiological conditions, glutamate (0.01 to 10 mM), Kaina... |
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Systemic administration of GMP induces anxiolytic-like behavior in rats.
Pharmacol. Biochem. Behav. 96 , 306-311, (2010) The glutamatergic system has received considerable attention over the last few years as potential target to develop anxiolytic drugs. Guanine based purines (GBPs) play an important neurmodulatory effect in the glutamatergic system. Several studies have shown ... |
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GMP prevents excitotoxicity mediated by NMDA receptor activation but not by reversal activity of glutamate transporters in rat hippocampal slices.
Brain Res. 1231 , 113-120, (2008) Glutamate is the main excitatory neurotransmitter in the mammalian nervous system and is essential for its normal functions. However, overstimulation of glutamatergic system due to hyperactivation of NMDA receptors and/or impairment of glutamate reuptake syst... |
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Upconverting Nanoparticles Prompt Remote Near-Infrared Photoactivation of Ru(II)-Arene Complexes.
Chemistry 22 , 2801-11, (2016) The synthesis and full characterisation (including X-ray diffraction studies and DFT calculations) of two new piano-stool Ru(II) -arene complexes, namely [(η(6) -p-cym)Ru(bpy)(m-CCH-Py)][(PF)6]2 (1) and [(η(6) -p-cym)Ru(bpm)(m-CCH-Py)][(PF)6]2 (2; p-cym=p-cym... |
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Volumetric and Viscometric Studies of Nucleosides, Nucleotides and Furanose Sugar in Aqueous Medium from 288.15 to 298.15 K. Singh, M et al.
Iran. J. Chem. Chem. Eng. 1st ed., 25 , 53-66, (2006)
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