N-NITROSO-DIPHENYLAMINE
N-NITROSO-DIPHENYLAMINE structure
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Common Name | N-NITROSO-DIPHENYLAMINE | ||
|---|---|---|---|---|
| CAS Number | 86-30-6 | Molecular Weight | 198.221 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 346.5±15.0 °C at 760 mmHg | |
| Molecular Formula | C12H10N2O | Melting Point | 65-66 °C | |
| MSDS | Chinese USA | Flash Point | 163.4±20.4 °C | |
| Symbol |
GHS06, GHS08 |
Signal Word | Danger | |
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Novel study on N-nitrosamines as risk factors of cardiovascular diseases.
Biomed Res. Int. 2014 , 817019, (2014) Millions of people are exposed daily to N-nitrosamines from different environmental sources. The present study aims at investigating the role of N-nitrosamines in the alteration of homocysteine, lipid profile, oxidative stress, paraoxonase activity, antioxida... |
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A salting out-acetonitrile homogeneous extraction coupled with gas chromatography-mass spectrometry method for the simultaneous determination of thirteen N-nitrosamines in skin care cosmetics.
J. Chromatogr. A. 1422 , 82-8, (2015) A sensitive gas chromatography-mass spectrometry method was established for the simultaneous determination of thirteen N-nitrosamines (NAs) in skin care cosmetics. The cosmetics samples were firstly dispersed by water and subsequently extracted and purified u... |
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A novel method for the identification of inorganic and organic gunshot residue particles of lead-free ammunitions from the hands of shooters using scanning laser ablation-ICPMS and Raman micro-spectroscopy.
Analyst 139(23) , 6232-41, (2014) A method based on scanning laser ablation and inductively coupled plasma-mass spectrometry (SLA-ICPMS) and Raman micro-spectroscopy for the detection and identification of compounds consistent with gunshot residue particles (GSR) has been developed. The metho... |
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Formation and cytotoxicity of a new disinfection by-product (DBP) phenazine by chloramination of water containing diphenylamine.
J. Environ. Sci. (China) 24(7) , 1217-24, (2012) Disinfection by-products (DBPs) in drinking water have caused worldwide concern due to their potential carcinogenic effects. The formation of phenazine from diphenylamine (DPhA) chloramination was studied and its cytotoxicities for two human cancer cells were... |
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Expedient liquid chromatographic assay for paclitaxel in plasma after its administration to cancer patients.
Ther. Drug Monit. 17(5) , 511-5, (1995) A rapid and expedient liquid chromatographic method for the analysis of paclitaxel in plasma is described. Paclitaxel and the internal standard (IS, N-nitrosodiphenylamine) were separated on a 10-microns particle, 8 mm x 10 cm C18 cartridge in conjunction wit... |
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Metabolic denitrosation of diphenylnitrosamine: a possible bioactivation pathway.
J. Cancer Res. Clin. Oncol. 113(2) , 131-6, (1987) Nitrosodiphenylamine was tested for induction of DNA single strand breaks in rat hepatocytes and Chinese hamster V 79 cells with the alkaline filter elution assay. While in rat hepatocytes DNA damage was observed, negative results were obtained in V 79 cells.... |
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Genotoxic effects of N-nitrosodicyclohexylamine in isolated human lymphocytes.
Arch. Toxicol. 75(2) , 118-22, (2001) Dicyclohexylamine x nitrite is classified as an "experimental equivocal tumorigenic agent" by the National Toxicology Program. Since no genotoxic effects of the substance itself are known, the reported tumorigenic potential of dicyclohexylamine x nitrite coul... |
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Quantitative bioassay using laser-monitored bacteria to assess toxicology and metabolism of bioactive Group IV compounds.
Sci. Total Environ. 112(2-3) , 177-88, (1992) A new approach has been developed for assessing the toxicity and the metabolism of Group IV compounds and for other toxic substances that may interact with them at the molecular level. The approach is based upon the selective responses of sensitive biodetecto... |
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Oxidation of 1,1-diphenylhydrazine to N-nitrosodiphenylamine by superoxide radical in the eye.
Jpn. J. Ophthalmol. 36(1) , 103-7, (1992) By microsomes obtained from bovine ciliary body, 1,1-diphenylhydrazine was oxidized to N-nitrosodiphenylamine in the presence of NADPH. This reaction was stimulated by riboflavin which was recognized to be an electron carrier. The oxidizing activity by micros... |
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Liquid chromatographic and thermal energy analyzer detection of N-nitrosodiphenylamine in formulations of diphenylamine.
Bull. Environ. Contam. Toxicol. 45(6) , 853-7, (1990)
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