N-Hydroxyphthalimide
N-Hydroxyphthalimide structure
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Common Name | N-Hydroxyphthalimide | ||
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| CAS Number | 524-38-9 | Molecular Weight | 163.130 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 370.3±25.0 °C at 760 mmHg | |
| Molecular Formula | C8H5NO3 | Melting Point | 233 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 177.8±23.2 °C | |
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Bromide-free oxidizing system for carboxylic moiety formation in cellulose chain.
Carbohydr. Polym. 90(4) , 1415-9, (2012) NHPI (N-hydroxyphthalimide) was used to mediate the oxidation of cellulose fibers in the absence of sodium bromide, as traditionally was used in this kind of transformations, solely using sodium hypochlorite (NaOCl) as the primary oxidant. Avoiding the use of... |
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Anthrone-derived NHPI analogues as catalysts in reactions using oxygen as an oxidant.
Org. Biomol. Chem. 6(22) , 4096-8, (2008) An enantioselective synthesis of anthrone-derived NHPI analogues has been developed. One of these analogues, in combination with Co salts, was employed to catalyse the aerobic oxidation of benzylic compounds and diols. Exploratory studies using a racemic vers... |
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Oxidized cellulose--survey of the most recent achievements.
Carbohydr. Polym. 93(1) , 207-15, (2013) The functionalization and particularly the oxidation of cellulose is an intriguing and challenging topic due to the presence of multiple reactive sites, which can undergo specific reactions. The variety of the oxidizing agents used to improve the selectivity ... |
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Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
Bioorg. Med. Chem. 17 , 569-75, (2009) One limitation of almost all antiviral Quantitative Structure-Activity Relationships (QSAR) models is that they predict the biological activity of drugs against only one species of virus. Consequently, the development of multi-tasking QSAR models (mt-QSAR) to... |
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Mild and selective oxidation of cellulose fibers in the presence of N-hydroxyphthalimide.
Biomacromolecules 10(8) , 2294-9, (2009) The oxidation reaction of regenerated cellulose fibers mediated by N-hydroxyphthalimide (NHPI) and various cocatalysts at room temperature for different time intervals and various amounts of low concentration sodium hypochlorite solution has been investigated... |
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Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations: optimizing for cyclization-trapping over cycloisomerization.
Org. Lett. 5(20) , 3595-8, (2003) [reaction: see text] Screening combinations of five catalyst precursors with 13 phosphorus ligands identified cyclization catalysts that favor carbocyclization-trapping with N-hydroxyphthalimide over a competing cycloisomerization mode. |
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Application of a dual linker with a reference cleavage site to discover a new reaction between amines and N-hydroxyphthalimide.
J. Comb. Chem. 7(4) , 523-5, (2005)
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Crystal growth and characterization of N-hydroxyphthalimide (C8H5NO3) crystal.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 71(1) , 110-5, (2008) Single crystals of N-hydroxyphthalimide (NHPH) were obtained from saturated aqueous solutions of methanol and acetonitrile by slow cooling method. The grown crystals were bright and transparent. From the crystal structure analysis it can be inferred that the ... |
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A kinetic study of the electron-transfer reaction of the phthalimide-N-oxyl radical (PINO) with ferrocenes.
J. Org. Chem. 72 , 8748, (2007) A kinetic study of the one-electron oxidation of a series of ferrocenes (FcX: X = H, CO2Et, CONH2, CH2CN, CH2OH, Et, and Me2) by PINO generated in CH3CN by reaction of N-hydroxyphthalimide (NHPI) with the cumyloxyl radical produced by 355 nm laser flash photo... |
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Fluorous tagged N-hydroxy phthalimide for the parallel synthesis of O-aryloxyamines.
J. Comb. Chem. 12 , 655-658, (2010) The parallel synthesis of O-aryloxyamines remains an unfulfilled need in the field of medicinal chemistry and fragment-based approaches. To fill this gap a solution-phase two-step process based on (1) a copper-catalyzed cross-coupling of aryl boronic acids wi... |