carbaryl
carbaryl structure
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Common Name | carbaryl | ||
|---|---|---|---|---|
| CAS Number | 63-25-2 | Molecular Weight | 201.221 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 366.5±25.0 °C at 760 mmHg | |
| Molecular Formula | C12H11NO2 | Melting Point | 142-146 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 175.4±23.2 °C | |
| Symbol |
GHS06, GHS08, GHS09 |
Signal Word | Danger | |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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Plant essential oils affect the toxicities of carbaryl and permethrin against Aedes aegypti (Diptera: Culicidae).
J. Med. Entomol. 50(4) , 826-32, (2013) ABSTRACT Phytochemicals have been considered as alternatives for conventional pesticides because of their low mammalian toxicity and environmental safety. They usually display less potent insecticidal effects than synthetic compounds, but may express as yet u... |
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Inhibition of Voltage-Gated Calcium Channels After Subchronic and Repeated Exposure of PC12 Cells to Different Classes of Insecticides.
Toxicol. Sci. 147 , 607-17, (2015) We previously demonstrated that acute inhibition of voltage-gated calcium channels (VGCCs) is a common mode of action for (sub)micromolar concentrations of chemicals, including insecticides. However, because human exposure to chemicals is usually chronic and ... |
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Polar organic chemical integrative samplers for pesticides monitoring: impacts of field exposure conditions.
Sci. Total Environ. 488-489 , 188-96, (2014) This study focuses on how Polar Organic Chemical Integrative Samplers (POCIS) work in real environmental conditions. A selection of 23 polar pesticides and 8 metabolites were investigated by exposure of triplicates of integrative samplers in two rivers in Fra... |
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Potential involvement of chemicals in liver cancer progression: an alternative toxicological approach combining biomarkers and innovative technologies.
Toxicol. In Vitro 28(8) , 1507-20, (2014) Pesticides as well as many other environmental pollutants are considered as risk factors for the initiation and the progression of cancer. In order to evaluate the in vitro effects of chemicals present in the diet, we began by combining viability, real-time c... |
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Highly selective biomarkers for pesticides developed in Eisenia fetida using SELDI-TOF MS.
Environ. Toxicol. Pharmacol. 39 , 635-42, (2015) The repeated use of pesticides, and their subsequent residues, has contributed to severe adverse effects on the environment, including risks to human health. Therefore, it is important to assess the quality of the environment to ensure it remains free from pe... |
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The role of methanol addition to water samples in reducing analyte adsorption and matrix effects in liquid chromatography-tandem mass spectrometry.
J. Chromatogr. A. 1389 , 76-84, (2015) Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis coupled simply with water filtering before injection has proven to be a simple, economic and time-saving method for analyzing trace-level organic pollutants in aqueous environments. However, t... |
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Use of in vitro data in developing a physiologically based pharmacokinetic model: Carbaryl as a case study.
Toxicology 332 , 52-66, (2015) In vitro-derived information has been increasingly used to support and improve human health risk assessment for exposure to chemicals. Physiologically based pharmacokinetic (PBPK) modeling is a key component in the movement toward in vitro-based risk assessme... |
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Effect of carbamate pesticides on perforin, granzymes A-B-3/K, and granulysin in human natural killer cells.
Int. J. Immunopathol. Pharmacol. 28 , 403-10, (2015) We previously found that ziram, a carbamate pesticide, significantly reduced perforin, granzyme A (GrA), granzyme B (GrB), granzyme 3/K (Gr3/K), and granulysin (GRN) levels in NK-92MI cells, a human natural killer (NK) cell line. To investigate whether other ... |
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Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors.
J. Med. Chem. 51 , 7327-43, (2008)
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