Thiophanate-methyl
Thiophanate-methyl structure
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Common Name | Thiophanate-methyl | ||
|---|---|---|---|---|
| CAS Number | 23564-05-8 | Molecular Weight | 342.39 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 478.4ºC at 760 mmHg | |
| Molecular Formula | C12H14N4O4S2 | Melting Point | 172°C | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS08, GHS09 |
Signal Word | Warning | |
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Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): Identification of phenmedipham and amperozide as FAAH inhibitors
Bioorg. Med. Chem. Lett. 19 , 6793-6, (2009) The screening of known medicinal agents against new biological targets has been shown to be a valuable approach for revealing new pharmacology of marketed compounds. Recently, carbamate, urea and ketone inhibitors of fatty acid amide hydrolase (FAAH) have bee... |
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New active drugs against liver stages of Plasmodium predicted by molecular topology.
Antimicrob. Agents Chemother. 52 , 1215-20, (2008) We conducted a quantitative structure-activity relationship (QSAR) study based on a database of 127 compounds previously tested against the liver stage of Plasmodium yoelii in order to develop a model capable of predicting the in vitro antimalarial activities... |
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Biological monitoring of pesticide exposures in residents living near agricultural land.
BMC Public Health 11 , 856, (2011) There is currently a lack of reliable information on the exposures of residents and bystanders to pesticides in the UK. Previous research has shown that the methods currently used for assessing pesticide exposure for regulatory purposes are appropriate for fa... |
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Molecular characterization of benzimidazole-resistant isolates of Cladosporium fulvum.
FEMS Microbiol. Lett. 278(2) , 242-8, (2008) The benzimidazole fungicide thiophanate-methyl is commonly applied to control leaf mould of tomato caused by Cladosporium fulvum in China. In this study, 32 isolates of C. fulvum were examined for their sensitivities to thiophanate-methyl, and two benzimidazo... |
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Determination of carbendazim, thiophanate, thiophanate-methyl and benomyl residues in agricultural products by liquid chromatography-tandem mass spectrometry.
Shokuhin Eiseigaku Zasshi 52(3) , 148-55, (2011) A simple and reliable liquid chromatographic-tandem mass spectrometric (LC-MS/MS) method was developed for carbendazim (MBC), thiophanate (TE), thiophanate-methyl (TM) and benomyl (BM) in agricultural products. These compounds were extracted from agricultural... |
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Fungicide methyl thiophanate binding at sub-domain IIA of human serum albumin triggers conformational change and protein damage
Int. J. Biol. Macromol. 47(1) , 60-7, (2010) Fluorescence quenching data on interaction of a fungicide methyl thiophanate (MT) with human serum albumin (HSA) elucidated a primary binding site at sub-domain IIA. Stern–Volmer algorithm and double log plot revealed the binding affinity ( K a) and capacity ... |
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The effects of the fungicide methyl thiophanate on adrenal gland morphophysiology of the lizard, Podarcis sicula.
Arch. Environ. Contam. Toxicol. 53(2) , 241-8, (2007) Endocrine-disrupting chemicals (EDCs) are a large group of substances able to modulate endocrine-signaling pathways, altering the normal function of the endocrine system. Although the fungicide methyl thiophanate (MT) is not considering a specific reproductiv... |
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Testicular toxicity of methyl thiophanate in the Italian wall lizard (Podarcis sicula): morphological and molecular evaluation.
Ecotoxicology 21(2) , 512-23, (2012) The effects of the fungicide methyl thiophanate (MT) on testis were determined in the Italian wall lizard (Podarcis sicula) using morphological and molecular analyzes. Three experimental trials were performed: an acute test using six doses, a two-week chronic... |
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Genotoxic fungicide methyl thiophanate as an oxidative stressor inducing 8-oxo-7,8-dihydro-2' -deoxyguanosine adducts in DNA and mutagenesis.
J. Environ. Sci. Health B 45(1) , 40-5, (2010) Dimethyl 4,4' -(O-phenylene)bis(3-thioallophanate), commonly known as methyl thiophanate (MT), is a systemic fungicide and suspected carcinogen to humans. In this study, the oxidative potential of this category-III acute toxicant has been ascertained based on... |
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Flower-inhabiting Frankliniella Thrips (Thysanoptera: Thripidae), pesticides, and Fusarium hardlock in cotton.
J. Econ. Entomol. 102(3) , 887-96, (2009) Cotton hardlock caused by Fusarium verticillioides (Sacc. Nirenberg) can reduce cotton, Gossypium hirsutum L., yields > 70% in the southeastern United States. The spores infect flowers on the day of pollination, resulting in hardlock, which is the failure of ... |