Spergualin trihydrochloride

Spergualin trihydrochloride Structure
Spergualin trihydrochloride structure
Common Name Spergualin trihydrochloride
CAS Number 80952-47-2 Molecular Weight 512.90300
Density N/A Boiling Point N/A
Molecular Formula C17H40Cl3N7O4 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Improved synthesis of 15-deoxyspergualin analogs using the Ugi multi-component reaction.

Bioorg. Med. Chem. Lett. 21(9) , 2587-90, (2011)

Spergualin is a natural product that exhibits immunosuppressive, anti-tumor and anti-bacterial activities. Its derivatives, such as 15-deoxyspergualin (15-DSG), have been clinically approved for acute allograft rejection. However, the reported syntheses are c...