5-Chlorooxindole
5-Chlorooxindole structure
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Common Name | 5-Chlorooxindole | ||
|---|---|---|---|---|
| CAS Number | 17630-75-0 | Molecular Weight | 167.592 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 348.3±42.0 °C at 760 mmHg | |
| Molecular Formula | C8H6ClNO | Melting Point | 194-197 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 164.5±27.9 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
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Assay and purity evaluation of 5-chlorooxindole by liquid chromatography.
J. Pharm. Biomed. Anal. 14(7) , 825-33, (1996) 5-Chlorooxindole (5-CO) is a starting material for tenidap sodium, a pharmaceutical drug candidate produced by Pfizer. To insure potency and purity of the drug substance, it is necessary to demonstrate that commercial supplies of 5-CO are free from elevated l... |
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Synthesis and biological evaluation of new pyridone-annelated isoindigos as anti-proliferative agents.
Molecules 19(9) , 13076-92, (2014) A selected set of substituted pyridone-annelated isoindigos 3a-f has been synthesized via interaction of 5- and 6-substituted oxindoles 2a-f with 6-ethyl-1,2,9-trioxopyrrolo[3,2-f]quinoline-8-carboxylic acid (1) in acetic acid at reflux. Among these isoindigo... |
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