D-Ornithine monohydrochloride
D-Ornithine monohydrochloride structure
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Common Name | D-Ornithine monohydrochloride | ||
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| CAS Number | 16682-12-5 | Molecular Weight | 168.622 | |
| Density | 1.165g/cm3 | Boiling Point | 308.7ºC at 760mmHg | |
| Molecular Formula | C5H13ClN2O2 | Melting Point | 239ºC (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 140.5ºC | |
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Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma.
Am. J. Respir. Cell. Mol. Biol. 48(6) , 694-702, (2013) Up-regulation of arginase contributes to airways hyperresponsiveness (AHR) in asthma by reducing L-arginine bioavailability for the nitric oxide (NO) synthase isozymes. The product of arginase activity, L-ornithine, can be metabolized into polyamines by ornit... |
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Microbacterium kyungheense sp. nov. and Microbacterium jejuense sp. nov., isolated from salty soil.
Int. J. Syst. Evol. Microbiol. 64(Pt 7) , 2267-73, (2014) Two novel strains, THG-C26(T) and THG-C31(T), were characterized using a polyphasic approach to determine their taxonomic positions. These two isolates were aerobic, Gram-stain-positive, non-motile, non-spore-forming and rod-shaped. 16S rRNA gene sequences an... |
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Influence of environmental hypertonicity on the induction of ureogenesis and amino acid metabolism in air-breathing walking catfish (Clarias batrachus, Bloch).
Indian J. Exp. Biol. 52(7) , 728-38, (2014) Effect of environmental hypertonicity, due to exposure to 300 mM mannitol solution for 7 days, on the induction of ureogenesis and also on amino acid metabolism was studied in the air-breathing walking catfish, C. batrachus, which is already known to have the... |
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A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes.
J. Biol. Chem. 289(49) , 34161-74, (2014) Cobalamin-dependent enzymes enhance the rate of C-Co bond cleavage by up to ∼10(12)-fold to generate cob(II)alamin and a transient adenosyl radical. In the case of the pyridoxal 5'-phosphate (PLP) and cobalamin-dependent enzymes lysine 5,6-aminomutase and orn... |
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Discovery of an Iron-Regulated Citrate Synthase inStaphylococcus aureus
Chem. Biol. 19(12) , 1568-78, (2012) Bacteria need to scavenge iron from their environment, and this is no less important for bacterial pathogens while attempting to survive in the mammalian host. One key strategy is the synthesis of small iron chelators known as siderophores. The study of sider... |
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Three-component lysine/ornithine decarboxylation system in Lactobacillus saerimneri 30a.
J. Bacteriol. 195(6) , 1249-54, (2013) Lactic acid bacteria play a pivotal role in many food fermentations and sometimes represent a health threat due to the ability of some strains to produce biogenic amines that accumulate in foods and cause trouble following ingestion. These strains carry speci... |
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Diversity-oriented synthesis of azapeptides with basic amino acid residues: aza-lysine, aza-ornithine, and aza-arginine.
Org. Lett. 16(13) , 3588-91, (2014) Aza-peptides with basic amino acid residues (lysine, ornithine, arginine) and derivatives were synthesized by an effective approach featuring alkylation of a hydrazone-protected aza-glycine residue with α-bromo ω-chloro propane and butane to provide the corre... |
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The G protein-coupled receptor family C group 6 subtype A (GPRC6A) receptor is involved in amino acid-induced glucagon-like peptide-1 secretion from GLUTag cells.
J. Biol. Chem. 288(7) , 4513-21, (2013) Although amino acids are dietary nutrients that evoke the secretion of glucagon-like peptide 1 (GLP-1) from intestinal L cells, the precise molecular mechanism(s) by which amino acids regulate GLP-1 secretion from intestinal L cells remains unknown. Here, we ... |
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Interorgan metabolism of ornithine phenylacetate (OP)--a novel strategy for treatment of hyperammonemia.
Biochem. Pharmacol. 85(1) , 115-23, (2013) Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought... |
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Effect of major and minor surgery on plasma levels of arginine, citrulline, nitric oxide metabolites, and ornithine in humans.
Ann. Surg. 258(6) , 1072-8, (2013) To determine the effect of surgical invasiveness on plasma levels of arginine, citrulline, ornithine, and nitric oxide (NO) in humans.Surgical trauma may have a profound effect on the metabolism of NO. However, human studies reported both increased and decrea... |