1,3-difluoro-2-propanol
1,3-difluoro-2-propanol structure
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Common Name | 1,3-difluoro-2-propanol | ||
|---|---|---|---|---|
| CAS Number | 453-13-4 | Molecular Weight | 96.07590 | |
| Density | 1.24 g/mL at 25 °C(lit.) | Boiling Point | 54-55 °C34 mm Hg(lit.) | |
| Molecular Formula | C3H6F2O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 108 °F | |
| Symbol |
GHS02, GHS07 |
Signal Word | Warning | |
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The mode of toxic action of the pesticide gliftor: the metabolism of 1,3-difluoroacetone to (-)-erythro-fluorocitrate.
J. Biochem. Mol. Toxicol. 15(1) , 47-54, (2001) The biochemical toxicology of 1,3-difluoroacetone, a known metabolite of the major ingredient of the pesticide Gliftor (1,3-difluoro-2-propanol), was investigated in vivo and in vitro. Rat kidney homogenates supplemented with coenzyme A, ATP, oxaloacetate, an... |
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Haloalcohols deplete glutathione when incubated with fortified liver fractions.
Xenobiotica 29(5) , 533-45, (1999) 1. This study has examined the ability of dichloropropanols, haloalcohols and their putative metabolites to deplete glutathione when incubated with liver fractions obtained from untreated and differentially induced rats. 2. 1,3-Dichloropropan-2-ol and 2,3-dic... |
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The biochemical toxicology of 1,3-difluoro-2-propanol, the major ingredient of the pesticide gliftor: the potential of 4-methylpyrazole as an antidote.
J. Biochem. Mol. Toxicol. 12(1) , 41-52, (1998) Administration to rats of 1,3-difluoro-2-propanol (100 mg kg-1 body weight), the major ingredient of the pesticide gliftor, resulted in accumulation of citrate in the kidney after a 3 hour lag phase. 1,3-Difluoro-2-propanol was found to be metabolized to 1,3-... |