Thymine-beta-D-arabinofuranoside
Thymine-beta-D-arabinofuranoside structure
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Common Name | Thymine-beta-D-arabinofuranoside | ||
|---|---|---|---|---|
| CAS Number | 605-23-2 | Molecular Weight | 258.23 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C10H14N2O6 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Image guided drug release from pH-sensitive Ion channel-functionalized stealth liposomes into an in vivo glioblastoma model.
Nanomedicine: Nanotechnology, Biology, and Medicine 11 , 1345-54, (2015) Liposomal drug delivery vehicles are promising nanomedicine tools for bringing cytotoxic drugs to cancerous tissues selectively. However, the triggered cargo release from liposomes in response to a target-specific stimulus has remained elusive. We report on f... |
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Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade.
Sci. Transl. Med. 7 , 315ra188, (2015) Targeted drug delivery with antibody-drug conjugates such as the HER2-directed ado-trastuzumab emtansine (T-DM1) has emerged as a powerful strategy for cancer therapy. We show that T-DM1 is particularly effective in eliciting antitumor immunity in patients wi... |
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iTRAQ-Based Quantitative Proteomic Analysis of Tear Fluid in a Rat Penetrating Keratoplasty Model With Acute Corneal Allograft Rejection.
Invest. Ophthalmol. Vis. Sci. 56 , 4117-24, (2015) This study aimed to develop a greater understanding of the mechanisms underlying acute corneal allograft rejection by identifying differentially expressed tear proteins at defined stages and discovering potentially important proteins involved in the process.T... |
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Probiotic fermented milk consumption modulates the allergic process induced by ovoalbumin in mice.
Br. J. Nutr. 114 , 566-76, (2015) Orally administered probiotic micro-organisms are able to regulate the exacerbated immune response during the antigenic sensitisation process. The aim of the present study was to evaluate the potential efficacy of probiotic fermented milk (PFM) in preventing ... |
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Mesenchymal stem cells improve motor functions and decrease neurodegeneration in ataxic mice.
Mol. Ther. 23(1) , 130-8, (2015) The main objective of this work is to demonstrate the feasibility of using bone marrow-derived stem cells in treating a neurodegenerative disorder such as Friedreich's ataxia. In this disease, the dorsal root ganglia of the spinal cord are the first to degene... |
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DNA vaccines encoding DEC205-targeted antigens: immunity or tolerance?
Immunology 145 , 519-33, (2015) Targeting of antigens to the endocytic uptake receptor DEC205 resulted in enhanced antigen presentation by dendritic cells (DCs). In combination with adjuvants for DC maturation, proteins coupled to an antibody against DEC205 induced strong pathogen-specific ... |
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A CD3-specific antibody reduces cytokine production and alters phosphoprotein profiles in intestinal tissues from patients with inflammatory bowel disease.
Gastroenterology 147(1) , 172-83, (2014) T cells mediate the development of inflammation in inflammatory bowel disease (IBD). We investigated the effects of an antibody against CD3 called otelixizumab, which induces immune tolerance, in intestinal mucosa samples from patients.Intestinal tissues were... |
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Adipose-derived mesenchymal stem cells embedded in platelet-rich fibrin scaffolds promote angiogenesis, preserve heart function, and reduce left ventricular remodeling in rat acute myocardial infarction.
Am. J. Transl. Res. 7 , 781-803, (2015) This study tested the hypothesis that autologous adipose-derived mesenchymal stem cells (ADMSCs) embedded in platelet-rich fibrin (PRF) can significant promote myocardial regeneration and repair after acute myocardial infarction (AMI).With avoiding the needle... |
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PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia.
Nat. Commun. 6 , 7514, (2015) Prostaglandin D2 (PGD2) is a major prostanoid secreted mainly by mast cells. Although PGD2 has been identified as a modulator of allergic inflammation, its precise role remains unclear. Here we investigate the role of PGD2 in food allergy. Oral administration... |
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Impact of an Energy Drink on the Structure of Stomach and Pancreas of Albino Rat: Can Omega-3 Provide a Protection?
PLoS ONE 11 , e0149191, (2016) A controversy developed between the benefits of energy drinks (EDs) versus the possible health threats since its revolution. Lack of information was a call to assess the effect of chronic consumption of Power Horse (PH) as one of the EDs, on the structure of ... |