2-Indanamine

2-Indanamine Structure
2-Indanamine structure
Common Name 2-Indanamine
CAS Number 2975-41-9 Molecular Weight 133.190
Density 1.1±0.1 g/cm3 Boiling Point 226.2±29.0 °C at 760 mmHg
Molecular Formula C9H11N Melting Point N/A
MSDS Chinese USA Flash Point 96.8±19.6 °C
Symbol GHS07
GHS07
Signal Word Warning

An investigation of the stability of emerging new psychoactive substances.

Drug Test. Anal. 6(7-8) , 696-704, (2014)

The evolving nature of new psychoactive substances (NPS) - often referred to as 'legal highs', 'designer drugs' or 'bath salts' - presents an evolving challenge for toxicologists. Apart from the detection and identification of these compounds, further analyti...

Wide-range screening of psychoactive substances by FIA-HRMS: identification strategies.

Anal. Bioanal. Chem 407 , 4567-80, (2015)

Recreational drugs (illicit drugs, human and veterinary medicines, legal highs, etc.) often contain lacing agents and adulterants which are not related to the main active ingredient. Serious side effects and even the death of the consumer have been related to...

Central cyanosis on a psychiatric unit treated at the Salford Royal Hospital.

Thorax 69(12) , 1157-8, (2014)

We describe a case of acquired methaemoglobinaemia due to frequent use of the 'legal high' known as 'Pink Panthers'. This contains 5,6-Methylenedioxy-2-aminoindane and 2-Aminoindane, both amphetamine analogues with the potential to cause methaemoglobinaemia. ...

Oxygen-18 studies on the oxidative deamination mechanism of alicyclic primary amines in rabbit liver microsomes.

Arch. Biochem. Biophys. 215(2) , 433-43, (1982)

Assessment of a potential dopaminergic prodrug moiety in several ring systems.

J. Med. Chem. 29(10) , 2016-20, (1986)

The ortho hydroxy/methyl, hydroxy/hydroxymethyl, hydroxy/formyl, and hydroxy/carboxy substitution patterns, some of which confer dopaminergic agonist effects upon 2-aminotetralin ring systems, have been incorporated into beta-phenethylamine, 2-aminoindan, and...

Synthesis, dopaminergic profile, and molecular dynamics calculations of N-aralkyl substituted 2-aminoindans.

Bioorg. Med. Chem. 16(6) , 3233-44, (2008)

Brain dopaminergic system has a crucial role in the etiology of several neuropsychiatric disorders, including Parkinson's disease, depression, and schizophrenia. Several dopaminergic drugs are used to treat these pathologies, but many problems are attributed ...

Dopaminergic structure-activity relationships of 2-aminoindans and cardiovascular action and dopaminergic activity of 4-hydroxy, 5-methyl, 2-di-n-propylaminoindan (RD-211).

J. Pharmacol. Exp. Ther. 256(2) , 751-6, (1991)

Dopaminergic structure-activity relationships of 2-aminoindans were evaluated for their ability to inhibit responses to stimulation of cardioaccelerator nerves in cats. The major observations were as follows: 1) Unsubstituted di-n-propyl- and diethyl 2-aminoi...

N-aralkyl substitution of 2-aminoindans. Synthesis and their inotropic and chronotropic activity in isolated guinea pig atria.

Arzneimittelforschung 47(11) , 1208-10, (1997)

Amino substitution of rigid forms of dopamine 4,5-dihydroxy-2-aminoindan and 5,6-dihydroxy-2-aminoindan with aralkyl functionalities were carried out to investigate the role of such structural modifications upon cardiac inotropic-chronotropic activity. Compou...

Comparison of biological effects of N-alkylated congeners of beta-phenethylamine derived from 2-aminotetralin, 2-aminoindan, and 6-aminobenzocycloheptene.

J. Med. Chem. 23(7) , 745-9, (1980)

Three series of bicyclic, semirigid congeners of beta-phenethylamine have been prepared for evaluation of the effect of ring size (and of concomitant conformational variation) on biological activity in a variety of assays for adrenergic and dopaminergic actio...

Conformations of 2-aminoindan in a supersonic jet: the role of intramolecular N-H...pi hydrogen bonding.

J. Phys. Chem. A 111(27) , 5981-7, (2007)

Laser-induced fluorescence (LIF), dispersed fluorescence (DF), mass-resolved one-color resonance enhanced two-photon ionization (RE2PI) and UV-UV hole-burning spectra of 2-aminoindan (2-AI) were measured in a supersonic jet. The hole-burning spectra demonstra...