2-Aminoacridone
2-Aminoacridone structure
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Common Name | 2-Aminoacridone | ||
|---|---|---|---|---|
| CAS Number | 27918-14-5 | Molecular Weight | 210.231 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 442.5±34.0 °C at 760 mmHg | |
| Molecular Formula | C13H10N2O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 221.4±25.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Complex influence of dermatan sulphate on breast cancer cells.
Exp. Biol. Med. (Maywood.) 239(12) , 1575-88, (2014) Tumor transformation and progression both lead to extracellular matrix remodeling, which is also reflected in an alteration in the proportion of dermatan sulphate (DS) and chondroitin sulphate (CS) and an accumulation of the latter. In addition, a significant... |
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FACE analysis as a fast and reliable methodology to monitor the sulfation and total amount of chondroitin sulfate in biological samples of clinical importance.
Molecules 19(6) , 7959-80, (2014) Glycosaminoglycans (GAGs) due to their hydrophilic character and high anionic charge densities play important roles in various (patho)physiological processes. The identification and quantification of GAGs in biological samples and tissues could be useful prog... |
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Hyaluronan in cervical epithelia protects against infection-mediated preterm birth.
J. Clin. Invest. 124(12) , 5481-9, (2014) Increased synthesis of cervical hyaluronan (HA) from early to late pregnancy has long been proposed to play an essential role in disorganization of the collagen-rich extracellular matrix to allow for maximal compliance and dilation of the cervix during the bi... |
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Profiling pneumococcal type 3-derived oligosaccharides by high resolution liquid chromatography-tandem mass spectrometry.
J. Chromatogr. A. 1397 , 43-51, (2015) Pneumococcal type-3 polysaccharide (Pn3P) is considered a major target for the development of a human vaccine to protect against Streptococcus pneumoniae infection. Thus, it is critical to develop methods for the preparation and analysis of Pn3P-derived oligo... |
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Comparative glycoprofiling of HIV gp120 immunogens by capillary electrophoresis and MALDI mass spectrometry.
Electrophoresis 36 , 1305-13, (2015) The human immunodeficiency virus (HIV) envelope glycoprotein (Env) is the primary antigenic feature on the surface of the virus and is of key importance in HIV vaccinology. Vaccine trials with the gp120 subunit of Env are ongoing, with the recent RV144 trial ... |
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Pharmaceutical grade chondroitin sulfate: Structural analysis and identification of contaminants in different commercial preparations.
Carbohydr. Polym. 134 , 300-8, (2015) The aim of the present study was to characterize 16 pharmaceutical grade chondroitin sulfate (CS) samples, concerning the structure and presence of contaminants, in comparison to USP and analytical grade CS. Agarose gel electrophoresis has shown that only 5 s... |
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Sialic acid speciation using capillary electrophoresis: optimization of analyte derivatization and separation.
Anal. Chem. 84(18) , 7638-42, (2012) Capillary electrophoresis with laser induced fluorescence detection (CE-LIF) was employed for rapid sialic acid speciation, facilitating the quantitative determination of N-glycolylneuraminic acid (Neu5Gc) and N-acetylneuraminic acid (Neu5Ac) on glycoproteins... |
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Large-scale preparation, purification, and characterization of hyaluronan oligosaccharides from 4-mers to 52-mers.
Glycobiology 12 , 421-6, (2002) Hyaluronan (HA) was depolymerized by partial digestion with testicular hyaluronidase and separated into size-uniform HA oligosaccharides from 4-mers to 52-mers by anion exchange chromatography after removal of the hyaluronidase. The purity and size of each HA... |
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The analysis of fluorophore-labeled carbohydrates by polyacrylamide gel electrophoresis.
Mol. Biotechnol. 5 , 101-23, (1996) The glycans of glycoconjugates mediate numerous important biological processes. Their separation and structural determination present considerable difficulties because of the small quantities that are available from biological sources and the inherent difficu... |
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Enhanced electrophoretic resolution of monosulfate glycosaminoglycan disaccharide isomers on poly(methyl methacrylate) chips.
Electrophoresis 28(3) , 414-21, (2007) To improve the separation of monosulfate glycosaminoglycan disaccharide isomers by microchip electrophoresis, we found that addition of 1,4-dioxane (DO) dramatically improved analyte resolution, probably due to solvation effects. Methylcellulose (MC) was test... |