Epiboxidine hydrochloride

Epiboxidine hydrochloride Structure
Epiboxidine hydrochloride structure
Common Name Epiboxidine hydrochloride
CAS Number 188895-96-7 Molecular Weight 178.23
Density 1.13g/cm3 Boiling Point 313.1ºC at 760mmHg
Molecular Formula C10H14N2O Melting Point N/A
MSDS Chinese USA Flash Point 143.2ºC

Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidine.

Eur. J. Pharmacol. 321 , 189-194, (1997)

Synthetic (+/-)-epiboxidine (exo-2-(3-methyl-5-isoxazolyl)-7-azabicyclo[2.2.1]heptane) is a methylisoxazole analog of the alkaloid epibatidine, itself a potent nicotinic receptor agonist with antinociceptive activity. Epiboxidine contains a methylisoxazolyl r...

Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation.

Biochemistry 50 , 1567-81, (2011)

We have developed a homogeneous time-resolved fluorescence resonance energy transfer (FRET)-based assay that detects the formation of HIV-1 integrase (IN) dimers. The assay utilizes IN monomers that express two different epitope tags that are recognized by th...