4-hydroxyestradiol
4-hydroxyestradiol structure
|
Common Name | 4-hydroxyestradiol | ||
|---|---|---|---|---|
| CAS Number | 5976-61-4 | Molecular Weight | 288.38100 | |
| Density | 1.248g/cm3 | Boiling Point | 468.6ºC at 760 mmHg | |
| Molecular Formula | C18H24O3 | Melting Point | >210ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | 220.6ºC | |
| Symbol |
GHS08 |
Signal Word | Warning | |
|
Leptin induces CYP1B1 expression in MCF-7 cells through ligand-independent activation of the ERα pathway.
Toxicol. Appl. Pharmacol. 277(1) , 39-48, (2014) Leptin, a hormone with multiple biological actions, is produced predominantly by adipose tissue. Among its functions, leptin can stimulate tumour cell growth. Oestrogen receptor α (ERα), which plays an essential role in breast cancer development, can be trans... |
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