(5a)-Cholestane

(5a)-Cholestane Structure
(5a)-Cholestane structure
Common Name (5a)-Cholestane
CAS Number 481-21-0 Molecular Weight 372.670
Density 0.9±0.1 g/cm3 Boiling Point 440.9±12.0 °C at 760 mmHg
Molecular Formula C27H48 Melting Point 78-80 °C
MSDS Chinese USA Flash Point 210.3±13.1 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Determination of Milk Fat Adulteration with Vegetable Oils and Animal Fats by Gas Chromatographic Analysis.

J. Food Sci. 80 , C1945-51, (2015)

This study assessed the potential application of gas chromatography (GC) in detecting milk fat (MF) adulteration with vegetable oils and animal fats and of characterizing samples by fat source. One hundred percent pure MF was adulterated with different vegeta...

Accelerated separation of GC-amenable lipid classes in plant oils by countercurrent chromatography in the co-current mode.

Anal. Bioanal. Chem 407 , 9019-28, (2015)

Triacylglycerols represent the major part (>90%) in most plant oils and have to be eliminated, when the minor compounds such as phytosterols or tocopherols should be analyzed. Here, we used an all liquid-liquid chromatographic technique, countercurrent chroma...

Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters.

J. Transl. Med. 13 , 278, (2015)

Berberine (BBR), as a new medicine for hyperlipidemia, can reduce the blood lipids in patients. Mechanistic studies have shown that BBR activates the extracellular-signal regulated kinase pathway by stabilizing low-density-lipoprotein receptor mRNA. However, ...

Inhibition of Cholesterol and Polyunsaturated Fatty Acids Oxidation through the Use of Annatto and Bixin in High-Pressure Processed Fish.

J. Food Sci. 80(8) , C1646-53, (2015)

Annatto and bixin, the main carotenoid of annatto seeds, were both found to inhibit cholesterol oxidation in minced herring (Clupea harengus) and minced mackerel (Scomber scombrus) during high pressure processing (600 MPa for 10 min) and subsequent chilled st...

Ezetimibe reduces plant sterol accumulation and favorably increases platelet count in sitosterolemia.

J. Pediatr. 166(1) , 125-31, (2015)

To assess if ezetimibe (EZE), a sterol-absorption inhibitor, improves platelet (PLT) count and size relative to its effect on plasma plant sterol (PS) in patients with sitosterolemia (STSL).Patients with STSL (5 males, 3 females, 16-56 years of age) receiving...

Changes in lipid substances in rice during grain development.

Phytochemistry 116 , 170-9, (2015)

Lipid substances, such as fatty acids, γ-oryzanol, policosanols, and tocol (tocopherol+tocotrienol), were investigated in two rice cultivars, Ilpum and Dasan, during rice development. In both cultivars, the lipid extract level decreased steadily after it reac...

LC-MS/MS-based quantification of cholesterol and related metabolites in dried blood for the screening of inborn errors of sterol metabolism.

Anal. Bioanal. Chem 407 , 5227-33, (2015)

Smith-Lemli-Opitz syndrome (SLOS) is an inherited metabolic disease in the cholesterol biosynthesis pathway which is characterised by accumulation of 7- and 8-dehydrocholesterol and by reduced cholesterol concentrations in all tissues and body fluids. With th...

Subcritical extraction of flaxseed oil with n-propane: Composition and purity.

Food Chem. 188 , 452-8, (2015)

Flaxseed (Linum usitatissimum L.) oil was obtained via subcritical n-propane fluid extraction (SubFE) under different temperatures and pressures with an average yield of 28% and its composition, purity and oxidative stability were compared to oils obtained vi...

Impaired liver function in Xenopus tropicalis exposed to benzo[a]pyrene: transcriptomic and metabolic evidence.

BMC Genomics 15 , 666, (2014)

Despite numerous studies suggesting that amphibians are highly sensitive to cumulative anthropogenic stresses, the role pollutants play in the decline of amphibian populations remains unclear. Amongst the most common aquatic contaminants, polycyclic aromatic ...

Cholesterol and stigmasterol within a sunflower oil matrix: Thermal degradation and oxysterols formation.

Steroids 99 , 155-60, (2015)

The characteristics of the lipid matrix surrounding sterols exert a great influence in their thermal oxidation process. The objective of this work was to assess the oxidation susceptibility of equal amounts of cholesterol and stigmasterol within a sunflower o...