N6-Cyclopentyladenosine
N6-Cyclopentyladenosine structure
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Common Name | N6-Cyclopentyladenosine | ||
|---|---|---|---|---|
| CAS Number | 41552-82-3 | Molecular Weight | 335.36 | |
| Density | 1.78g/cm3 | Boiling Point | 673.4ºC at 760 mmHg | |
| Molecular Formula | C15H21N5O4 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 361.1ºC | |
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The effect of pH and ion channel modulators on human placental arteries.
PLoS ONE 9(12) , e114405, (2014) Chorionic plate arteries (CPA) are located at the maternofetal interface where they are able to respond to local metabolic changes. Unlike many other types of vasculature, the placenta lacks nervous control and requires autoregulation for controlling blood fl... |
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Acid-sensing ion channel 3 decreases phosphorylation of extracellular signal-regulated kinases and induces synoviocyte cell death by increasing intracellular calcium.
Arthritis. Res. Ther. 16(3) , R121, (2014) Acid-sensing ion channel 3 (ASIC3) is expressed in synoviocytes, activated by decreases in pH, and reduces inflammation in animal models of inflammatory arthritis. The purpose of the current study was to characterize potential mechanisms underlying the contro... |
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Chemoenzymatic Syntheses of Sialylated Oligosaccharides Containing C5-Modified Neuraminic Acids for Dual Inhibition of Hemagglutinins and Neuraminidases.
Chemistry 21 , 10903-12, (2015) A fast chemoenzymatic synthesis of sialylated oligosaccharides containing C5-modified neuraminic acids is reported. Analogues of GM3 and GM2 ganglioside saccharidic portions where the acetyl group of NeuNAc has been replaced by a phenylacetyl (PhAc) or a prop... |
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Store-operated calcium entry compensates fast ER calcium loss in resting hippocampal neurons.
Cell Calcium 58 , 147-59, (2015) The endoplasmic reticulum (ER) acts as a dynamic calcium store and is involved in the generation of specific patterns of calcium signals in neurons. Calcium is mobilized from the ER store by multiple signaling cascades, and neuronal activity is known to regul... |
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Membranes as a possible pacemaker of metabolism in cypriniform fish: does phylogeny matter?
J. Exp. Biol. 218 , 2563-72, (2015) The 'membrane pacemaker theory of metabolism' proposes that membranes set metabolic rate by modulating protein activity, and thus purports to explain membrane fatty acid allometry. This relationship has never been tested across species in ectotherms. After ac... |
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Slow and steady cell shrinkage reduces osmotic stress in bovine and murine oocyte and zygote vitrification.
Hum. Reprod. 30(1) , 37-45, (2014) Does the use of a new cryoprotectant agent (CPA) exchange protocol designed to minimize osmotic stress improve oocyte or zygote vitrification by reducing sublethal cryodamage?The use of a new CPA exchange protocol made possible by automated microfluidics impr... |
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Acute toxicity and genotoxicity study of fermented traditional herb formula Guibi-tang.
J. Ethnopharmacol. 156 , 182-9, (2014) Guibi-tang (Guipi-tang in Chinese and Kihi-to in Japanese) is a multi-herb traditional medicine commonly prescribed to treat psychoneurosis in East Asia. Although this medicine has been widely used, there is little available information on the safety and toxi... |
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Pre-clinical in vitro and in vivo safety evaluation of bovine whey derived osteopontin, Lacprodan® OPN-10.
Food Chem. Toxicol. 73 , 59-70, (2014) Lacprodan® OPN-10 is a proprietary whey-based protein product that contains bovine-derived osteopontin (OPN), found in human milk and other bodily tissues. In vitro genotoxicity tests conducted according to accepted guidelines at up to 5000μg/plate OPN failed... |
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Genotoxicity of rice bran oil extracted by supercritical CO2 extraction.
Biol. Pharm. Bull. 37(12) , 1963-70, (2014) Rice bran oil extracted by supercritical CO2 extraction (RB-SCE) reportedly exhibits pharmacological activities such as antioxidant and in vivo hair growth-inducing effects. Such activities raise the possibility of the development of novel hair growth-inducin... |
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Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering.
EMBO J. 34 , 2291-305, (2015) The extended synaptotagmins (E-Syts) are ER proteins that act as Ca(2+)-regulated tethers between the ER and the plasma membrane (PM) and have a putative role in lipid transport between the two membranes. Ca(2+) regulation of their tethering function, as well... |