Ochratoxin A
Ochratoxin A structure
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Common Name | Ochratoxin A | ||
|---|---|---|---|---|
| CAS Number | 303-47-9 | Molecular Weight | 403.813 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 632.4±55.0 °C at 760 mmHg | |
| Molecular Formula | C20H18ClNO6 | Melting Point | 169ºC | |
| MSDS | Chinese USA | Flash Point | 336.3±31.5 °C | |
| Symbol |
GHS06, GHS08 |
Signal Word | Danger | |
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Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
J. Biol. Chem. 282 , 23841-53, (2007) Organic anion transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding ... |
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Role of microRNA-29b in the ochratoxin A-induced enhanced collagen formation in human kidney cells.
Toxicology 324 , 116-22, (2014) Ochratoxin A (OTA) is an ubiquitous mycotoxin suspected to cause fibrotic kidney diseases. The involvement of mircoRNAs in these processes is unknown. Here, we investigated the role of the anti-fibrotic miR-29b in OTA-induced alterations of cellular collagen ... |
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Development of a stir bar sorptive extraction method for analysis of ochratoxin A in beer.
J. AOAC Int. 97(4) , 1092-6, (2014) A new, simple, and sensitive method was developed for extraction of ochratoxin A (OTA) in beer combined with HPLC-fluorescence detector. Samples were extracted by stir bar sorptive extraction (SBSE) followed by liquid desorption using commercially available T... |
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Relationship between ecophysiological factors, growth and ochratoxin A contamination of dry-cured sausage based matrices.
Int. J. Food Microbiol. 194 , 71-7, (2015) Dry-cured sausages are colonised by moulds during the ripening process. The temperature and the salt content (which affects water activity, aw) predispose the surface to colonisation by Penicillium species, including Penicillium nordicum and Penicillium verru... |
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The influence of salt (NaCl) on ochratoxin A biosynthetic genes, growth and ochratoxin A production by three strains ofPenicillium nordicumon a dry-cured ham-based medium
Int. J. Food Microbiol. 178 , 113-9, (2014) Iberian dry-cured ham is colonised by moulds during the ripening process. The environmental conditions occurring during the process including the salt content predisposes the surface to colonisation by Penicillium species, including Penicillium nordicum which... |
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Oxidative stress induces the biosynthesis of citrinin by Penicillium verrucosum at the expense of ochratoxin.
Int. J. Food Microbiol. 192 , 1-6, (2015) Penicillium verrucosum is a fungus that can produce ochratoxin A and citrinin, two structurally related nephrotoxic mycotoxins. P. verrucosum usually occurs on wheat but can occasionally also be found in NaCl rich habitats such as salted cheeses or olives, in... |
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Development of nanogold-based lateral flow immunoassay for the detection of ochratoxin A in buffer systems.
J. Nanosci. Nanotechnol. 13(11) , 7245-9, (2013) Ochratoxin A (OTA), classified as a possible human renal carcinogen (group 2B), is a potent toxin as to cause the nephropathy. Many methods have been proposed and reviewed for OTA determination in food and agricultural products. However, current analytical pr... |
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Determination of aflatoxins, deoxynivalenol, ochratoxin A and zearalenone in wheat and oat based bran supplements sold in the Spanish market.
Food Chem. Toxicol. 53 , 133-8, (2013) The aflatoxins (AFs), deoxynivalenol (DON), ochratoxin A (OTA) and zearalenone (ZEA) are mycotoxins produced by fungal species which can contaminate, alone or simultaneously, cereal-based raw materials. Usually, the higher mycotoxins concentrations in cereals... |
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In vitro study on the effect of Saccharomyces cerevisiae strains on growth and mycotoxin production by Aspergillus carbonarius and Fusarium graminearum.
Int. J. Food Microbiol. 161(3) , 182-8, (2013) The effect of Saccharomyces cerevisiae RC008 and RC016 strains, previously selected based on their aflatoxin B₁ mycotoxin binding ability and beneficial properties, against Aspergillus carbonarius and Fusarium graminearum under different interacting environme... |
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Multi-component immunochromatographic assay for simultaneous detection of aflatoxin B1, ochratoxin A and zearalenone in agro-food.
Biosens. Bioelectron. 49 , 426-32, (2013) Mycotoxins are highly toxic contaminants and have induced health threat to human and animals. Aflatoxin B1 (AFB1), ochratoxin A (OTA) and zearalenone (ZEA) commonly occur in food and feed. A multi-component immunochromatographic assay (ICA) was developed for ... |