SB408124
SB408124 structure
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Common Name | SB408124 | ||
|---|---|---|---|---|
| CAS Number | 288150-92-5 | Molecular Weight | 356.369 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 430.3±45.0 °C at 760 mmHg | |
| Molecular Formula | C19H18F2N4O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 214.0±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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A major role for perifornical orexin neurons in the control of glucose metabolism in rats.
Diabetes 58(9) , 1998-2005, (2009) The hypothalamic neuropeptide orexin influences (feeding) behavior as well as energy metabolism. Administration of exogenous orexin-A into the brain has been shown to increase both food intake and blood glucose levels. In the present study, we investigated th... |
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Hypocretin/orexin type 1 receptor in brain: role in cardiovascular control and the neuroendocrine response to immobilization stress.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 292(1) , R382-7, (2007) Hypocretin/orexin acts pharmacologically in the hypothalamus to stimulate stress hormone secretion at least in part by an action in the hypothalamic paraventricular nucleus, where the peptide's receptors have been localized. In addition, orexin acts in the br... |
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Modulation of respiratory activity by hypocretin-1 (orexin A) in situ and in vitro.
Adv. Exp. Med. Biol. 669 , 109-13, (2010) Release of hypocretins (orexins) by neurons in the lateral hypothalamus is an important contributor to arousal state, thermoregulation, feeding behavior, and has recently been proposed to play a role in breathing and central chemosensitivity. Using the in sit... |