TRAP-14 trifluoroacetate salt
TRAP-14 trifluoroacetate salt structure
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Common Name | TRAP-14 trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 137339-65-2 | Molecular Weight | 1739.92000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C81H118N20O23 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Soluble expression and purification of receptor activator of nuclear factor-kappa B ligand using Escherichia coli.
J. Microbiol. Biotechnol. 25(2) , 274-9, (2015) Receptor activator of nuclear factor-kappa B ligand (RANKL) is a critical factor in osteoclastogenesis. It makes osteoclasts differentiate and multinucleate in bone remodeling. In the present study, RANKL was expressed as a soluble maltose binding protein (MB... |
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The biocompatibility of degradable magnesium interference screws: an experimental study with sheep.
Biomed Res. Int. 2015 , 943603, (2015) Screws for ligament reconstruction are nowadays mostly made of poly-L-lactide (PLLA). However, magnesium-based biomaterials are gathering increased interest in this research field because of their good mechanical property and osteoanabolic influence on bone m... |
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CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines.
Cancer Res. 74(23) , 7103-14, (2014) Src family kinases (SFK) integrate signal transduction for multiple receptors, regulating cellular proliferation, invasion, and metastasis in human cancer. Although Src is rarely mutated in human prostate cancer, SFK activity is increased in the majority of h... |
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Bleeding diathesis and gastro-duodenal ulcers in inherited cytosolic phospholipase-A2 alpha deficiency.
Thromb. Haemost. 112(6) , 1182-9, (2014) Arachidonic acid (AA), when cleaved from phospholipids by cytosolic phospholipase A2 alpha (cPLA2a), generates eicosanoids, with pro-hemostatic, pro-inflammatory, vasoactive and gastro-protective functions. We describe a patient (27-year-old man) and his twin... |
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Pasteurella multocida toxin- induced osteoclastogenesis requires mTOR activation.
Cell Commun. Signal. 13 , 40, (2015) Pasteurella multocida toxin (PMT) is a potent inducer of osteoclast formation. Pigs suffering from an infection with toxigenic Pasteurella multocida strains develop atrophic rhinitis characterised by a loss of turbinate bones and conchae. However, on the mole... |
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Impaired extracellular matrix structure resulting from malnutrition in ovariectomized mature rats.
Histochem. Cell Biol. 144 , 491-507, (2015) Bone loss is a symptom related to disease and age, which reflects on bone cells and ECM. Discrepant regulation affects cell proliferation and ECM localization. Rat model of osteoporosis (OVX) was investigated against control rats (Sham) at young and old ages.... |
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Impact of prophylactic CpG Oligodeoxynucleotide application on implant-associated Staphylococcus aureus bone infection.
Bone 78 , 194-202, (2015) TLR-9 ligand CpG oligodeoxynucleotide type B (CpG ODN) induces a proinflammatory environment. We evaluated the effects of a preoperative CpG ODN application in an implant-associated Staphylococcus aureus bone infection model by monitoring bacterial loads and ... |
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Local administration of stromal cell-derived factor-1 promotes stem cell recruitment and bone regeneration in a rat periodontal bone defect model.
Mater. Sci. Eng. C. Mater. Biol. Appl. 53 , 83-94, (2015) Stromal cell-derived factor-1 (SDF-1) recruits adult stem/progenitor cells via its specific receptor, C-X-C motif receptor 4 (CXCR4), to promote heart, kidney and tendon regeneration, but little is known about the effects of SDF-1 on bone regeneration in peri... |
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Effects of extracellular magnesium extract on the proliferation and differentiation of human osteoblasts and osteoclasts in coculture.
Acta Biomater. 27 , 294-304, (2015) Coculture of osteoblasts and osteoclasts is a subject of interest in the understanding of how magnesium (Mg)-based implants influence the bone metabolism and remodeling upon degradation. Human telomerase reverse transcriptase (hTERT) transduced mesenchymal st... |
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ISG15 regulates RANKL-induced osteoclastogenic differentiation of RAW264 cells.
Biol. Pharm. Bull. 38(3) , 482-6, (2015) Interferon-stimulated gene 15 kDa (ISG15) is a protein upregulated by interferon-β that negatively regulates osteoclastogenesis. We investigated the role of ISG15 in receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenic differentiati... |